Despite advances in treatment and prevention, malaria still carries significant morbidity and mortality. Cases of malaria in the United States are rare and cases of severe malaria, mostly attributable to , are even more uncommon. With the coronavirus disease 2019 (COVID-19) pandemic, there have been distractions in evaluation and diagnosis leading to a rise in cases and deaths. We present a case of autoimmune dysregulation and blackwater fever secondary to severe malaria, requiring multiple courses of antimalarial therapy. Careful travel history and prompt recognition and treatment facilitates improved patient survival and recovery.
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http://dx.doi.org/10.7759/cureus.25458 | DOI Listing |
BMC Med Educ
January 2025
Department of International Public Health, Emergency Obstetric and Quality of Care Unit, Liverpool School of Tropical Medicine, Pembrooke Place, L3, 5QA, Liverpool, UK.
Background: The blended learning (BL) approach to training health care professionals is increasingly adopted in many countries because of high costs and disruption to service delivery in the light of severe human resource shortage in low resource settings. The Covid-19 pandemic increased the urgency to identify alternatives to traditional face-to-face (f2f) education approach. A four-day f2f antenatal care (ANC) and postnatal care (PNC) continuous professional development course (CPD) was repackaged into a 3-part BL course; (1) self-directed learning (16 h) (2) facilitated virtual sessions (2.
View Article and Find Full Text PDFSaudi Med J
January 2025
From the Department of Pediatrics (Imam, Musa), University of Maiduguri Teaching Hospital; from the Department of Pediatrics (Elechi, Rabasa), College of Medical Sciences, University of Maiduguri, Maiduguri; and from the Department of Pediatrics (Bakari), College of Medical Sciences, Modibo Adama University, Yola, Nigeria.
Objectives: To determine the prevalence and pattern of hypoglycemia among children admitted to the Emergency Pediatric Unit (EPU) at the University of Maiduguri Teaching Hospital, Maiduguri, Nigeria.
Methods: A cross-sectional study was conducted between February and September 2020. Blood glucose, along with other relevant laboratory investigations, was measured for each patient upon admission to the EPU using a point-of-care test glucometer (ACCU-CHEK with strips).
Int J Surg Case Rep
January 2025
Faculty of Medicine and Health Sciences, Omdurman Islamic University, Sudan.
Introduction: Spontaneous rupture of the pathological malarial spleen (SRPMS) is a rare condition with a mortality rate among travelers of approximately 38 %, whereas it was around 10 % for local citizens. The mortality rate for overwhelming post-splenectomy sepsis was reported to be about 50 %.
Methods: A retrospective study was conducted from febraury2022 to July 2022.
Pediatr Infect Dis J
December 2024
Division of Infectious Diseases, Department of Pediatrics, University of Mississippi Medical Center.
We assessed severe acute respiratory syndrome coronavirus 2 seroprevalence on residual blood samples for pediatric COVID-19 surveillance: 2263 samples were collected during routine outpatient visits (<18 years, April 2020-August 2021). Seroprevalence increased over time, coinciding with or preceding virus circulation in the community and with or preceding pediatric severe COVID-19 hospitalization peaks. Residual blood sample seroprevalence may be a useful surveillance tool in future outbreaks.
View Article and Find Full Text PDFBiosci Biotechnol Biochem
January 2025
Department of Bioresource Science, Faculty of Agriculture.
Plasmodium falciparum is a major cause of severe malaria. This protozoan infects human red blood cells and secretes large quantities of histidine-rich protein 2 (PfHRP2) into the bloodstream, making it a well-known diagnostic marker. Here, however, we identified PfHRP2 as a pathogenic factor produced by P.
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