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Resisting Newton in provincial France, 1750s-1770s: Opposition from the margins to the Parisian academic community.
Stud Hist Philos Sci
December 2024
Université Libre de Bruxelles, Avenue F. Roosevelt 50, 1050, Bruxelles, Belgium. Electronic address:
In the eighteenth century, the requirements for participation in scientific life were progressively narrowed, leading to a gradual closure of the community of the learned. This shift was influenced by the dissemination of Newton's natural philosophy across Europe, which catalysed the rejection of previously dominant principles and methods, while heralding the adoption of a new approach, based on mathematics and experimentalism. This paper examines various forms of resistance to the emergence of a community of Newtonian savants in post-1750 France, focusing on institutions and authors located at its margins.
View Article and Find Full Text PDFFrom Classical to Alternative Pathways of 2-Arachidonoylglycerol Synthesis: AlterAGs at the Crossroad of Endocannabinoid and Lysophospholipid Signaling.
Molecules
August 2024
Infinity-Toulouse Institute for Infectious and Inflammatory Diseases, University of Toulouse, INSERM, CNRS, Paul Sabatier University, 31059 Toulouse, France.
2-arachidonoylglycerol (2-AG) is the most abundant endocannabinoid (EC), acting as a full agonist at both CB1 and CB2 cannabinoid receptors. It is synthesized on demand in postsynaptic membranes through the sequential action of phosphoinositide-specific phospholipase Cβ1 (PLCβ1) and diacylglycerol lipase α (DAGLα), contributing to retrograde signaling upon interaction with presynaptic CB1. However, 2-AG production might also involve various combinations of PLC and DAGL isoforms, as well as additional intracellular pathways implying other enzymes and substrates.
View Article and Find Full Text PDF[Developments in forensic medicine: the example of Haute-Normandie].
Rev Prat
April 2024
Ancien chef de service de médecine légale (IML-CASA) au CHU de Rouen, Rouen, France Professeur honoraire, Université de Rouen Rouen, France Membre titulaire de l'Académie des sciences, belles-lettres et arts de Rouen.
Dermatology in Ancient Rome: Medical ingredients in Ovid's "Remedies for female faces".
J Cosmet Dermatol
June 2020
Institute of the History, Philosophy and Ethics of Medicine, Ulm University, Ulm, Germany.
Background: In Roman medicine, face packs, plasters, unguents, and peelings were part of the therapy of dermatological diseases, but also served cosmetic purposes. Ancient medical textbooks inform us about the ingredients for these applications. Beyond medical literature, other genres contain information about dermatological applications.
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