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Recognition of the ABNM by the NRC.
J Nucl Med
July 2022
American Board of Nuclear Medicine Executive Director.
(Nano)tag-antibody conjugates in rapid tests.
J Mater Chem B
July 2021
Nanosensors Bioplatforms Laboratory, Chemistry and Chemical Engineering Research Center of Iran, 14335-186, Tehran, Iran.
Antibodies (Abs) are naturally derived materials with favorable affinity, selectivity, and fast binding kinetics to the respective antigens, which enables their application as promising recognition elements in the development of various types of biosensors/bioassays, especially in rapid tests. These tests are low-cost and easy-to-use biosensing devices with broad applications including medical or veterinary diagnostics, environmental monitoring and industrial usages such as safety and quality analysis in food, providing on-site quick monitoring of various analytes, making it possible to save analysis costs and time. To reach such features, the conjugation of Abs with various nanomaterials (NMs) as tags is necessary, which range from conventional gold nanoparticles to other nanoparticles recently introduced, where magnetic, plasmonic, photoluminescent, or multi-modal properties play a critical role in the overall performance of the analytical device.
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