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Reversible subcortical Dark White Matter lesions in nonconvulsive status epilepticus: a rare but clinically significant finding.
Acta Neurol Belg
December 2024
Lamezia Terme Hospital, Catanzaro, Italy.
[Case of ictal aphasia and post-ictal aphasia due to focal epilepsy associated with cerebral hemorrhage].
Rinsho Shinkeigaku
December 2024
Department of Neurology, Nakamura Memorial Hospital.
The patient was a 69-year-old right-handed woman. She had sensory aphasia, and the brain MRI revealed a subacute phase hemorrhage in the left subcortical temporal lobe. We speculated that the patient had post-ictal aphasia due to symptomatic epileptic seizures associated with cerebral hemorrhage.
View Article and Find Full Text PDFRefractory and Super-Refractory Status Epilepticus: Therapeutic Options and Prognosis.
Neurol Clin
February 2025
Department of Neurology, University of Lausanne, Lausanne, Switzerland. Electronic address:
In patients with status epilepticus (SE), the underlying biologic background represents the main prognostic variable. A swift application of a treatment protocol is recommended, including adequate doses of a benzodiazepine followed by an intravenous anti-seizure medicine. If refractory SE arises, general anesthetics should be used in generalized convulsive and non-convulsive SE in coma, while further non-sedating anti-seizure medications attempts are warranted in patients with focal forms.
View Article and Find Full Text PDFUtility of CT perfusion in seizures and rhythmic and periodic patterns.
Clin Neurophysiol
December 2024
Department of Neurology, Johns Hopkins Bayview Medical Center, Baltimore, MD 21224, USA; Epilepsy Center, Department of Neurology, The Johns Hopkins Hospital, Baltimore, MD 21287, USA. Electronic address:
Objective: CT hyper-perfusion has been reported in non-convulsive status epilepticus (NCSE), while its occurrence and relevance after single seizures or with rhythmic and periodic patterns (RPPs) that lie along the ictal-interictal continuum (IIC), remain unclear. The goal of the study is to assess the role of CT perfusion (CTP) in diagnosing patients with clinical seizures, subclinical seizures, or RPPs that lie along the IIC, to help in the clinical assessment of these entities.
Methods: We retrospectively reviewed inpatients who underwent a CTP and an EEG within 6 h of each other.
The long-term effects of limbic non-convulsive status epilepticus in peri-adolescent rats.
Epilepsy Behav
December 2024
Stark Neurosciences Research Institute, Indiana University School of Medicine, Indianapolis, IN, United States; Department of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, Lebanon; Division of Child Neurology, Department of Neurology, Indiana University School of Medicine, Riley Hospital for Children, Indianapolis, IN, United States. Electronic address:
To optimize the clinical approach to non-convulsive status epilepticus (NCSE), it is essential to gain insight into its long-term effects on cognition and behaviors. Here, we investigated limbic NCSE-induced hippocampal injury and behavioral deficits in peri-adolescent rats. NCSE was induced in P43 Sprague Dawleyrats with intrahippocampal subconvulsive doses of kainic acid (NCSE group, n = 14) under continuous epidural cortical electroencephalography (EEG).
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