Cardiac troponin (cTn) can also be elevated in patients with non-cardiac illnesses. The utility of elevated cTn in patients with acute gastrointestinal bleeding (AGIB) is unclear. We retrospectively identified all patients admitted with AGIB who had cTn ordered. We assessed the prevalence, predictors and mortality. A total of 172 patients with AGIB were included in the study, of whom 17% had abnormal cTn. Predictors of elevated cTn were advanced age, lower BMI, coronary artery disease and chronic kidney disease. The abnormal cTn group had more cardiac consultation and procedures and longer length of stay. However, there was no difference in mortality between the two groups. Elevated cTn in patients with AGIB was associated with more cardiology consultation and downstream cardiac testing, greater delay to endoscopic evaluation and longer length of stay, without significantly affecting the mortality.
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http://dx.doi.org/10.2217/fca-2021-0143 | DOI Listing |
Clin Neurol Neurosurg
December 2024
Department of Neurosurgery, People's Hospital of Yubei District of Chongqing City, Chongqing, China.
Objective: Myocardial injury has not been well characterized in traumatic brain injury (TBI). We aimed to assess the pooled incidence of myocardial injury defined by elevated cardiac troponin (cTn) after TBI and explore its association with in-hospital mortality.
Methods: We searched Medline, Embase, Cochrane Library, Scopus, and Web of Science from inception to 1 January 2024, for observational studies that assessed the incidence and/or associated in-hospital mortality of elevated cTn in adult TBI patients.
Front Cardiovasc Med
November 2024
Postgraduate Research Program, Harvard Medical School, Boston, MA, United States.
Cardiovascular disease (CVD), including atherosclerosis, valvular etiologies, or myocardial disorders, is typically asymptomatic for several years, representing an occult phase of illness. Readily available preventive treatments to reduce cholesterol and blood pressure, among other risk factors, have the potential to reduce and delay incident myocardial infarction (MI), heart failure, and cardiovascular (CV) deaths. Measurement of circulating levels of cardiac troponin T (cTnT) and troponin I (cTnI) released from cardiomyocytes, as a result of injury, has been the biochemical standard for the diagnosis of MI for more than 20 years.
View Article and Find Full Text PDFChest
October 2024
Royal Brompton and Harefield Hospitals and National Heart and Lung Institute, Imperial College London, London, England.
Medicina (Kaunas)
October 2024
Department of Cardiology, 'Dr. Carol Davila' Central Military Emergency University Hospital, 010825 Bucharest, Romania.
Stroke-heart syndrome (SHS), a critical yet underrecognized condition, encompasses a range of cardiac complications that arise following an ischemic stroke. This narrative review explores the pathophysiology, clinical manifestations, and implications of SHS, focusing on the complex interplay between the brain and the heart. Acute ischemic stroke (AIS) triggers autonomic dysfunction, leading to a surge in catecholamines and subsequent myocardial injury.
View Article and Find Full Text PDFHealthcare (Basel)
October 2024
Independent Researcher, Atlanta, GA 30079, USA.
Pulmonary hypertension (PH) can lead to cardiac failure, thereby significantly affecting life expectancy and quality of life. Due to inadequate disease surveillance and risk assessment, clinical challenges persist despite advances in diagnosis and treatment. We aimed to review the potential of high-sensitivity cardiac troponin (hs-cTn) as a biomarker for predicting outcomes in PH patients.
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