Objective: This study analyzed changes in prescription opioid street prices during the COVID-19 pandemic.
Methods: Crowdsourced prescription opioid street prices were obtained from the Researched Abuse, Diversion and Addiction-Related Surveillance System StreetRx Program. Percentage changes in street price per milligram of different opioids between April and December 2020 compared with the same months in 2019 were calculated by using linear regression.
Results: Street prices of high-potency drugs hydromorphone and oxycodone increased 23% and 12% per milligram, respectively. Prices of low-potency drugs hydrocodone and morphine increased 9% and 12% per milligram, respectively. Changes in prices of medications for opioid use disorder were not statistically significant.
Conclusions: Decreased access to opioid analgesics during the pandemic combined with contributors to opioid demand may have led to increases in street prices of prescription opioids. Measures taken to increase access to medications for opioid use disorder were not associated with changes in those drugs' street prices.
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http://dx.doi.org/10.1176/appi.ps.202100689 | DOI Listing |
Ir J Med Sci
January 2025
Department of Clinical Microbiology, Children's Health Ireland at Temple Street Children's University Hospital, Dublin 1, Ireland.
Background: Lab users should display an understanding of microbiology tests and avoid inappropriate requests which may yield negative clinical consequences. Our research addressed diagnostic stewardship education and the perspectives of paediatric hospital doctors on their (1) self-perceived knowledge, (2) motivators for test ordering, (3) proposed educational interventions and (4) preferred teaching modalities.
Methods: An anonymous, mixed-methods, 34-item online questionnaire was distributed to paediatric doctors across three Irish hospital sites from March to May 2023.
BMC Pregnancy Childbirth
January 2025
Centre for Maternal and Child Health Research, City St George's, University of London, Myddelton Street Building, 1 Myddelton Street, London, EC1R 1UB, United Kingdom.
Background: In the United Kingdom, induction of labour rates are rapidly rising, and around a third of pregnant women undergo the procedure. The first stage, cervical ripening, traditionally carried out in hospital, is increasingly offered outpatient - or 'at home'. The current induction of labour rates place considerable demand on maternity services and impact women's experiences of care, and at home cervical ripening has been suggested as potential solution for alleviating these.
View Article and Find Full Text PDFSci Rep
January 2025
School of Management, Shandong Second Medical University, No. 7166, Baotong West Street, Weifang, 261053, Shandong, China.
This study examines the impact of micro-level land prices on corporate carbon emission intensity and identifies the underlying mechanisms. Using a unique dataset of Chinese industrial enterprises from 2000 to 2014, we employ a two-way fixed effects econometric model, alongside instrumental variable and Difference-in-Differences (DID) techniques, to address endogeneity concerns. Our findings reveal that a 1% increase in land prices leads to a 0.
View Article and Find Full Text PDFBrain Inform
January 2025
Department of Neurology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 02114, USA.
Cognitive resilience (CR) describes the phenomenon of individuals evading cognitive decline despite prominent Alzheimer's disease neuropathology. Operationalization and measurement of this latent construct is non-trivial as it cannot be directly observed. The residual approach has been widely applied to estimate CR, where the degree of resilience is estimated through a linear model's residuals.
View Article and Find Full Text PDFSupport Care Cancer
January 2025
Division of Hematology, Oncology, and Transplantation, University of Minnesota, 516 Delaware Street SE, MMC 480, PWB 14-100, Minneapolis, MN, 55455, USA.
Purpose: As cancer care is increasingly delivered in the home, more tasks and responsibilities fall on patients and their informal care partners. These time costs can present significant mental, physical, and financial burdens, and are undercounted in current measures of time toxicity that only consider care received in formal healthcare settings.
Methods: Semi-structured qualitative interviews were conducted with patients with gastrointestinal cancer and informal care partners at a single tertiary cancer center between March and October 2023.
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