In recent years, the development and exploration of deeper and more complex deep learning models has been on the rise. However, the availability of large heterogeneous datasets to support efficient training of deep learning models is lacking. While linear image transformations for augmentation have been used traditionally, the recent development of generative adversarial networks (GANs) could theoretically allow us to generate an infinite amount of data from the real distribution to support deep learning model training. Recently, the Radiological Society of North America (RSNA) curated a multiclass hemorrhage detection challenge dataset that includes over 800,000 images for hemorrhage detection, but all high-performing models were trained using traditional data augmentation techniques. Given a wide variety of selections, the augmentation for image classification often follows a trial-and-error policy. We designed conditional DCGAN (cDCGAN) and in parallel trained multiple popular GAN models to use as online augmentations and compared them to traditional augmentation methods for the hemorrhage case study. Our experimentations show that the super-minority, epidural hemorrhages with cDCGAN augmentation presented a minimum of improvement in their performance against the traditionally augmented model using the same classifier configuration. This shows that for complex and imbalanced datasets, traditional data imbalancing solutions may not be sufficient and require more complex and diverse data augmentation methods such as GANs to solve.
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http://dx.doi.org/10.1117/1.JMI.9.3.035504 | DOI Listing |
Blood Cancer Discov
January 2025
Princess Máxima Center, Utrecht, Netherlands.
In pediatric hematopoietic cell transplantation (HCT) recipients, transplanted donor cells may need to function far beyond normal human lifespan. Here, we investigated the risk of clonal hematopoiesis (CH) in 144 pediatric long-term HCT survivors and 258 non-transplanted controls. CH was detected in 16% of HCT recipients and 8% of controls, at variant allele frequencies (VAFs) of 0.
View Article and Find Full Text PDFEur Radiol Exp
January 2025
Nuffield Department of Clinical Neurosciences, University of Oxford, Oxford, OX3 9DU, UK.
Cerebral microbleeds (CMBs) are small, hypointense hemosiderin deposits in the brain measuring 2-10 mm in diameter. As one of the important biomarkers of small vessel disease, they have been associated with various neurodegenerative and cerebrovascular diseases. Hence, automated detection, and subsequent extraction of clinically useful metrics (e.
View Article and Find Full Text PDFArch Dermatol Res
January 2025
Department of Dermatology, Kocaeli University Faculty of Medicine, Kocaeli, Türkiye.
Introduction: Psoriasis is a chronic inflammatory skin disorder affecting millions worldwide. Dermoscopy and proximal nailfold capillaroscopy have emerged as valuable tools for understanding the pathophysiology and treatment response of psoriasis lesions.
Objectives: This study aimed to contribute to the limited literature on using dermoscopic findings to detect treatment effectiveness in patients with psoriasis vulgaris.
Mikrochim Acta
January 2025
College of Medical Technology, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
An innovative colorimetric sensing strategy was developed for the detection of glucose by the integration of glucose aptamer, glucose oxidase (GOx), and horseradish peroxidase (HRP), termed aptamer proximal enzyme cascade reactions (APECR). In the presence of glucose, aptamer binding enables GOx to catalyze glucose oxidation into HO efficiently. Subsequently, the adjacent HRP catalyzes the oxidation of the peroxidase substrate, 2,2'-biazobis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), utilizing the generated HO, resulting in a distinct color change.
View Article and Find Full Text PDFInsights Imaging
January 2025
Department of Diagnostic, Interventional and Paediatric Radiology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Objectives: This study aimed to evaluate whether minimum-intensity projection (MinIP) images could predict complications in CT-guided lung biopsies.
Methods: We retrospectively analyzed 72 procedures from January 2019 to December 2023, categorizing patients by pneumothorax and the severity of hemorrhage (grade 2 or higher). Radiodensity measurements were performed using lung window (LW) and MinIP (10-mm slab) images.
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