[This retracts the article DOI: 10.2147/OTT.S257747.].
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LINC01436 Promotes the Progression of Gastric Cancer via Regulating miR-513a-5p/APE1 Axis [Retraction].
Onco Targets Ther
June 2022
[This retracts the article DOI: 10.2147/OTT.S257747.
View Article and Find Full Text PDFLINC01436 Promotes the Progression of Gastric Cancer via Regulating miR-513a-5p/APE1 Axis.
Onco Targets Ther
October 2020
Department of Gastrointestinal Surgery and General Surgery, First Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui, People's Republic of China.
Background: Gastric cancer (GC) is one of the deadliest cancer worldwide. Multiple long non-coding RNAs (lncRNAs) are recently identified as crucial oncogenic factors or tumor suppressors in GC. In this study, we aimed to probe into the effect of LINC01436 on GC progression.
View Article and Find Full Text PDFLINC01436 Inhibited miR-585-3p Expression and Upregulated MAPK1 Expression to Promote Gastric Cancer Progression.
Dig Dis Sci
June 2021
Department of Oncology, The First Affiliated Hospital of Xi'an Jiaotong University, No. 277 West Yanta Road, Xi'an, 710061, Shaanxi, China.
Background: Gastric cancer (GC) is a prevalent type of digestion system malignancies. Dysregulation of long non-coding RNAs (lncRNAs) has been proven to be prognostic factors and biological regulators in human cancers.
Aims: The current study aimed to explore the role of long intergenic non-protein coding RNA 1436 (LINC01436) and its underlying mechanism in the progression of GC.
LINC01436, regulating miR-585 and FBXO11, is an oncogenic lncRNA in the progression of gastric cancer.
Cell Biol Int
March 2020
Department of Gastroenterology, Puren Hospital of Wuhan, Wuhan University of Science and Technology, 430081, Wuhan, China.
Accumulating studies have indicated that long non-coding RNAs (lncRNAs) are crucial modulators in cancer biology. In this work, we investigated the function and related mechanisms of LINC01436 in the progression of gastric cancer (GC). We demonstrated that LINC01436 was significantly up-regulated in cancerous tissues of GC samples, and its overexpression was correlated with a worse prognosis for the patients.
View Article and Find Full Text PDFHypoxia-sensitive LINC01436 is regulated by E2F6 and acts as an oncogene by targeting miR-30a-3p in non-small cell lung cancer.
Mol Oncol
April 2019
Department of Epidemiology, College of Preventive Medicine, Army Medical University (Third Military Medical University), Chongqing, China.
Dysregulation of long noncoding RNA (lncRNA) is known to be involved in numerous human diseases, including lung cancer. However, the precise biological functions of most lncRNA remain to be elucidated. Here, we identified a novel up-regulated lncRNA, LINC01436 (RefSeq: NR_110419.
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