Ascorbate- and NADPH-dependent free radical oxidation, the state of the antioxidant system, hydrogen iron secretion rate (HISR) and acid production kinetic function (AFKF) were investigated in 38 patients with duodenal ulcer to study the effect of hyperbaric oxygenation on free radical processes and gastric acid production. Assessment of the results of the study indicated the activation of NADPH-dependent free radical lipid oxidation, HISR acceleration and AFKF enhancement during hyperbaric oxygenation in the treatment of duodenal ulcer which required adjuvant corrective therapy.

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