AI Article Synopsis
- Pseudomyxoma peritonei (PMP) is a rare medical condition, and this study focused on its prevalence and incidence in China due to limited data from developing countries.
- A total of 153 PMP cases were analyzed, revealing a crude prevalence of 2.47 per million person-years in 2016, with higher rates in females and increasing age, peaking in those over 80.
- The findings indicate that PMP rates are lower in China compared to Europe, and there's a significant challenge in understanding this rare disease, which complicates evaluating its impact.
Article Abstract
Background: Pseudomyxoma peritonei (PMP) is an extremely rare condition. Information regarding the disease burden of PMP in developing countries is limited. This study aimed to determine the epidemiology of PMP in China.
Methods: PMP data were extracted from the national databases of Urban Basic Medical Insurance. All cases were identified using the International Classification of Diseases (ICD) codes and Chinese diagnostic terms. The national prevalence from 2012 to 2016 and incidence in 2016 were estimated.
Results: In total, 153 patients with PMP were identified. The crude prevalence of PMP in 2016 was 2.47 (95% confidence interval [CI] 1.71 to 3.23) per million person-year, with a higher prevalence in females than males. Prevalence increased with age, with the first peak in those aged 15-29 years and the highest in those aged >80 years. The crude incidence of PMP in 2016 was 1.19 (95% CI 0.59 to 1.78) per million person-years. Similar to the prevalence, the rates were higher in women than in men. The incidence also increased with age, with the highest prevalence in those aged >80 years. Besides, the most frequent comorbidities before and after the first diagnosis of PMP were unspecified secondary malignancies and malignancies of unspecified sites, followed by abdominal malignant tumours.
Conclusions: The rate of PMP was lower in mainland China than in European countries and increased with advancing age. Women were more likely to have PMP than men. Furthermore, an insufficient understanding of this rare disease presents a major challenge in accurately evaluating the disease burden.
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| http://dx.doi.org/10.1016/j.ejso.2022.06.013 | DOI Listing |
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