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Brucellosis causing bone marrow aplasia in an 11-year-old patient with complete recovery after treatment. | LitMetric

AI Article Synopsis

  • Brucellosis is a common zoonotic infection in the Middle East, presenting symptoms from mild fever to serious organ-related issues.
  • An eleven-year-old girl initially diagnosed with "idiopathic bone marrow aplasia" was found to have high brucella titers during her pre-transplant evaluation.
  • She was treated with doxycycline, rifampin, and gentamicin, and made a full recovery after eight months of treatment.

Article Abstract

Brucellosis is one of the most prevalent zoonotic infections in the Middle East. The disease may present with a range of symptoms from a simple febrile illness to severe invasive infections affecting different organ systems (meningitis, osteomyelitis). In this paper we present an eleven-year-old girl who was diagnosed with "idiopathic bone marrow aplasia" and planned for hematopoietic stem cell transplant (HSCT), when pre-transplant work-up showed high brucella titers. The patient was started on doxycycline, rifampin and gentamicin initially, with discontinuation of the latter 3 weeks into therapy. She recovered completely after 8 months of treatment.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9233216PMC
http://dx.doi.org/10.1016/j.idcr.2022.e01531DOI Listing

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