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http://dx.doi.org/10.1038/s41579-022-00765-2 | DOI Listing |
Unlabelled: Strain-level variation among host-associated bacteria often determines host range and the extent to which colonization is beneficial, benign, or pathogenic. is a beneficial symbiont of the light organs of fish and squid with known strain-specific differences that impact host specificity, colonization efficiency, and interbacterial competition. Here, we describe how the conserved global regulator, H-NS, has a strain-specific impact on a critical colonization behavior: biofilm formation.
View Article and Find Full Text PDFInt J Mol Sci
November 2024
School of Chemical Engineering, Yeungnam University, Gyeongsan 38541, Republic of Korea.
, prevalent in hospital and community settings, forms biofilms that are highly resistant to antibiotics and immune responses, complicating treatment and contributing to chronic infections. These challenges underscore the need for novel treatments that target biofilm formation and effectively reduce bacterial virulence. This study investigates the antibiofilm and antimicrobial efficacy of novel halogenated pyrimidine derivatives against , focusing on three compounds identified as potent biofilm inhibitors: 2,4-dichloro-5-fluoropyrimidine (24DC5FP), 5-bromo-2,4-dichloro-7H-pyrrolo[2,3-d]pyrimidine (24DC5BPP), and 2,4-dichloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine (24DC5IPP).
View Article and Find Full Text PDFACS Omega
December 2024
Department of Biotechnology, University of Chemistry and Technology, Prague 166 28, Czech Republic.
Silver nanoparticles (AgNPs) are excellent antimicrobial agents and promising candidates for preventing or treating bacterial infections caused by antibiotic resistant strains. However, their increasing use in commercial products raises concerns about their environmental impact. In addition, traditional physicochemical approaches often involve harmful agents and excessive energy consumption, resulting in AgNPs with short-term colloidal stability and silver ion leaching.
View Article and Find Full Text PDFFoods
November 2024
College of Food Science and Engineering, Nanjing University of Finance and Economics, Nanjing 210023, China.
biofilm contamination on food contact surfaces is a major concern for the food industry. Nanoparticle encapsulation appears as a novel strategy for food surface disinfection to prevent biofilm formation. Chitosan nanoparticles loaded with nisin and DNase I (DNase-CS-N) have been constructed to exhibit antimicrobial activity against .
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Federal University of Pernambuco, Av. Prof. Moraes Rego, 1235 - Cidade Universitária, 50670-901, Recife, Pernambuco, Brazil; Federal Rural University of Pernambuco, Street Dom Manuel de Medeiros, s/n - Dois Irmãos, 52171-900, Recife, Pernambuco, Brazil. Electronic address:
The aim of this study was to select the best exopolysaccharide (EPS) producer among the Enterococcus strains to optimize, characterize, and evaluate its biological properties. Among the eleven strains, Enterococcus faecium KT990028 was selected, and the production conditions were optimized: 16.3 % (w/v) sucrose, 0.
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