• A reduction in hemolysis with voxelotor analog, GBT1118, reduced hemoglobinuria and kidney injury biomarkers in transgenic sickle mice. • Improved chronic hemolysis preserved kidney function and histopathologic and ultrastructural changes in transgenic sickle mice.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9636314 | PMC |
| http://dx.doi.org/10.1182/bloodadvances.2022007809 | DOI Listing |
Publication Analysis
Top Keywords
transgenic sickle
12
sickle mice
12
mice •
8
improvement hemolytic
4
hemolytic anemia
4
anemia gbt1118
4
gbt1118 renoprotective
4
renoprotective transgenic
4
• reduction
4
reduction hemolysis
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!