Insufficient production of erythropoietin (EPO) leads to anaemia. Developing methods for the generation and transplantation of EPO-producing cells would allow scientists to design personalised therapeutic solutions. Here we present a simple and highly reproducible protocol for the generation of neural crest cells (NCCs) that can produce and secrete erythropoiesis-competent EPO in response to hypoxia.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9214825 | PMC |
| http://dx.doi.org/10.1016/j.mex.2022.101753 | DOI Listing |
Publication Analysis
Top Keywords
protocol generation
8
neural crest
8
crest cells
8
generation epo
4
epo producing
4
producing neural
4
cells
4
cells human
4
human induced
4
induced pluripotent
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!