In this study, twenty novel pyrimidine derivatives bearing a 1,3,4-thiadiazole skeleton were designed and synthesized. Then their antifungal activity against (), (), and sp. were determined using the poison plate technique. Biological test results showed that compound revealed lower EC values (25.9 and 50.8 μg/ml) on sp. than those of pyrimethanil (32.1 and 62.8 μg/ml).
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9213879 | PMC |
| http://dx.doi.org/10.3389/fchem.2022.922813 | DOI Listing |
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