Eosinophilic Granulomatosis with Polyangiitis.

Int J Appl Basic Med Res

Department of Pharmacology, Dr. DY Patil Medical College, Navi Mumbai, Maharashtra, India.

Published: May 2022

Eosinophilic granulomatosis with polyangiitis also known as Churg-Strauss syndrome or allergic granulomatosis and angiitis is an extremely rare systemic necrotizing vasculitis that affects small-to-medium-sized vessels. Here, we report a case of a 58-year-old man presenting with painful swelling of bilateral lower limbs with multiple well-defined erosions on lower legs and dorsum of the foot with a few of them showing brownish crusts and with slight watery discharge and a few with raw areas. The patient is a known case of bronchial asthma. Histopathology of foot and face lesion shows inflammatory cell infiltrate predominantly comprising of eosinophils, small- and medium-sized blood vessels are thickened. P-antineutrophil cytoplasmic antibody positivity was seen. Thus, on the basis of positive findings which satisfy the criteria for eosinophilic granulomatosis with polyangiitis, we diagnosed this as a case of eosinophilic granulomatosis with polyangiitis, and for rarity of this case, we would like to report it.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9215177PMC
http://dx.doi.org/10.4103/ijabmr.ijabmr_528_21DOI Listing

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