Background: Low back pain is one of the most common musculoskeletal diseases in the modern society, causing a huge economic burden, and has become an important public health problem. Years lived with disability caused by low back pain increased rapidly as a result of population growth and ageing worldwide, with the biggest increase seen in low-income and middle-income countries. In this context, the prevention and treatment of low back pain in the elderly warrant attention and research.
Objective: The aim is to determine the correlation between vital capacity (VC) and vertebral body translation during lumbar flexion and extension in adults aged 60 to 69 years.
Methods: A total of 192 adults aged 60 to 69 years were selected by cluster sampling in Lishui City, Zhejiang Province, China. The VC of the study population was tested and the ratio of VC to body mass (BM) was calculated. The lumbar hyperextension and hyperflexion of the study population were radiographed using a Hitachi 500 mAs X-ray machine made in Japan to verify vertebral body translations in each segment.
Results: The differences of test values of VC (P= 0.004), VC/BM ratio (P= 0.012) and vertebral body translation in the L5-S1 segment during flexion and extension (P< 0.001) of the populations aged 60 to 64 and 65 to 69 years were all statistically significant. The vertebral body translation in the L5-S1 segment during lumbar flexion and extension in the population aged 60 to 69 years was negatively correlated with the VC (rs =-0.207 and P= 0.004) and VC/BM ratio (rs =-0.248 and P= 0.001), showing statistical significance.
Conclusions: The vertebral body translation of during lumbar flexion and extension correlates with the VC in the population aged 60 to 69 years. Recognition of this correlation may help to guide further lumbar stabilization exercises.
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http://dx.doi.org/10.3233/BMR-210323 | DOI Listing |
ALTEX
January 2025
Laboratory of Hepato-Gastroenterology, Institute of Experimental and Clinical Research, UCLouvain, Brussels, Belgium.
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Healthy Longevity Translational Research Program, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.
Ageing is the primary driver of age-associated chronic diseases and conditions. Asian populations have traditionally been underrepresented in studies understanding age-related diseases. Thus, the Ageing BIOmarker Study in Singaporeans (ABIOS) aims to characterise biomarkers of ageing in Singaporeans, exploring associations between molecular, physiological, and digital biomarkers of ageing.
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Department of Psychiatry and Psychotherapy, University Clinic, Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen, Germany.
Schizophrenia is a chronic and severe mental disorder. It is currently treated with antipsychotic drugs (APD). However, APD's work only in a limited number of patients and may have cognition impairing side effects.
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January 2025
Cardio-Thoracic Translational Medicine (CTTM) Lab, Department of Surgical Sciences, Uppsala University, Uppsala, Sweden.
Recent developments in mass spectrometry-based proteomics have established it as a robust tool for system-wide analyses essential for pathophysiological research. While post-mortem samples are a critical source for these studies, our understanding of how body decomposition influences the proteome remains limited. Here, we have revisited published data and conducted a clinically relevant time-course experiment in mice, revealing organ-specific proteome regulation after death, with only a fraction of these changes linked to protein autolysis.
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