[Systematic reviews in five steps: I. Framing questions to obtain valid answers].

Semergen

CIBER de Epidemiología y Salud Pública (CIBERESP), Madrid, España; Unidad de Bioestadística Clínica, Hospital Ramón y Cajal, Madrid, España; Institute of Metabolism and Systems Research, University of Birmingham, Birmingham, Reino Unido.

Published: July 2022

This is the first in a series of five articles on the steps to follow to conduct a successful systematic review. This first article addresses how to formulate the right questions to initiate a systematic review. The key issues are: how to structure the questions appropriately according to the main components: the participants, the interventions or exposures compared, the outcomes measured and the study design; how to anticipate and consider possible variations in each of the components that may arise during the review; and finally, how to prospectively register the protocol of the systematic review.

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http://dx.doi.org/10.1016/j.semerg.2021.12.005DOI Listing

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