Objective: To study the discriminatory ability of the change (delta) in the Score for Neonatal Acute Physiology-II (SNAP-II) for 14-d mortality in preterm neonates with severe sepsis.
Methods: Consecutively born neonates of < 34-wk gestation during the 1-y study period in a tertiary care neonatal unit were included. SNAP-II was recorded at the onset of severe sepsis (T0) and serially at 24 (T1), 48 (T2), and 72 (T3) h. Delta scores (Δ SNAP-II) were derived from the difference between the SNAP-II at baseline and each one of the subsequent time points.
Results: Seventy-one preterm neonates were enrolled. Baseline characteristics were similar in survivors (n = 53) and nonsurvivors (n = 18). Median SNAP-II at all the four time points were significantly higher in nonsurvivors (p < 0.001). Delta SNAP-II (T0-T2) was significantly different between nonsurvivors and survivors (mean difference: -14.7; 95% CI: -29, -0.9; p = 0.02), while the difference was not significant between T0-T1 and T0-T3. Initial SNAP-II had a significantly better discriminating ability than Δ SNAP-II at various time points (AUC, 95% CI: 0.59, 0.41-0.75 for T0-T1; 0.70, 0.50-0.87 for T0-T2; and 0.64; 0.38-0.89 for T0-T3).
Conclusions: Delta SNAP-II does not have a better discriminatory ability for mortality by 14 d in preterm neonates with severe sepsis.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s12098-022-04190-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
The effect of mindfulness-based counselling on the anxiety levels and childbirth satisfaction among primiparous pregnant women: a randomized controlled trial.
BMC Psychiatry
December 2024
Social Development & Health Promotion Research Center, Health Institute, Kermanshah University of Medical Sciences, Kermanshah, Iran.
Background: Anxiety during pregnancy is linked to adverse maternal and neonatal outcomes, as well as dissatisfaction with childbirth, and may contribute to the development of postpartum depression. This study aimed to evaluate the effect of mindfulness-based counselling on the anxiety levels and childbirth satisfaction among primiparous pregnant women.
Methods: This two-group, parallel, randomized controlled trial involved 60 eligible primiparous pregnant women who were referred to health centers in Kermanshah province (western Iran).
Correlation between the 5-tier fetal heart rate pattern classification at delivery and Apgar scores.
J Obstet Gynaecol Res
January 2025
Department of Obstetrics and Gynecology, Yamagata University Faculty of Medicine, Yamagata, Yamagata, Japan.
Aim: In Japan, the fetal heart rate pattern on cardiotocography is usually categorized into five levels for intrapartum management; however, studies on the 5-tier cardiotocography classification are limited. This study aimed to determine the correlation between 5-tier cardiotocography levels at delivery, neonatal Apgar scores and perinatal prognosis using a perinatal registry database.
Methods: This retrospective study used the 2018 Perinatal Registry Database of the Japan Society of Obstetrics and Gynecology.
Fetal Characteristics and Perinatal Outcomes in Tetralogy of Fallot Without a Ductus Arteriosus.
Pediatr Cardiol
December 2024
Division of Cardiology, Department of Pediatrics, Stanford University School of Medicine, Lucile Packard Children's Hospital, Palo Alto, CA, USA.
Absence of the ductus arteriosus (DA) is common in tetralogy of Fallot (TOF), occurring in up to 30% of cases. Yet, the clinical course and fetal echocardiographic features are not well described, limiting prenatal counseling. This study examines the fetal echocardiographic characteristics and perinatal outcomes in children with TOF absent DA (TOF/ADA), comparing them to those with a DA (TOF/DA).
View Article and Find Full Text PDFRisk of autism spectrum disorder at 18 months of age is associated with prenatal level of polychlorinated biphenyls exposure in a Japanese birth cohort.
Sci Rep
December 2024
Graduate School of Advanced Science and Engineering, Hiroshima University, 1-4-1 Kagamiyama, Higashi-hiroshima, Hiroshima, 739-8527, Japan.
Prenatal exposure to polychlorinated biphenyls (PCBs) has a detrimental effect on early cognitive development. Based on these observations, some researchers suggested that prenatal exposure to PCB may be an environmental cause of autism spectrum disorder (ASD). To investigate the potential link between prenatal exposure to PCB, we analyzed the link between the level of prenatal PCB exposure and ASD risk evaluated at 18 months of age and behavioral problems at 5 years old based on longitudinal birth cohort data collected in urban areas in Japan based on the data from 115 mother-infant pairs.
View Article and Find Full Text PDFEffect of freezing and thawing on ejaculated sperm and subsequent pregnancy and neonatal outcomes in IVF.
Front Endocrinol (Lausanne)
December 2024
Department of Assisted Reproduction, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Background: Techniques for sperm cryopreservation have exhibited their potential in male fertility preservation. The use of frozen-thawed sperm in fertilization (IVF) cycles is widespread today. However, many studies reported that cryopreservation might have adverse effects on sperm DNA integrity, motility, and fertilization, probably due to cold shock, intra- and extracellular ice crystals, and excess reactive oxygen species (ROS).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!