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| http://dx.doi.org/10.1186/s13643-022-02009-z | DOI Listing |
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Race-Based Pulmonary Function Testing Correction in COPD Inhaler Therapy Trials: A Systematic Review.
Int J Chron Obstruct Pulmon Dis
October 2024
Faculty of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Purpose: Race-based correction is widely utilized in clinical practice, but may contribute to overestimation of lung function, underdiagnoses in minority groups, and exclusion of minority groups from research trials. The aim of this systematic review is to examine the usage of race-based correction in pulmonary function testing (PFT) within chronic obstructive lung disease (COPD) research and its impact on the exclusion of minority groups from research trials.
Methods: We systematically searched Medline from 2010 to 2022 to identify randomized controlled trials (RCTs) that examine inhaler therapy for COPD.
Correction: Edmonton's Race-based Data Table: A municipal approach to addressing systemic racism through the collection and use of disaggregated, race-based data.
Can J Public Health
October 2024
School of Public Health, University of Alberta, Edmonton, AB, Canada.
The race-based stress reduction intervention (RiSE) study on African American women in NYC and Chicago: Design and methods for complex genomic analysis.
PLoS One
April 2024
Marcella Niehoff School of Nursing, Center for Translational Research and Education, Loyola University Chicago, Maywood, Illinois, United States of America.
RiSE study aims to evaluate a race-based stress-reduction intervention as an effective strategy to improve coping and decrease stress-related symptoms, inflammatory burden, and modify DNA methylation of stress response-related genes in older AA women. This article will describe genomic analytic methods to be utilized in this longitudinal, randomized clinical trial of older adult AA women in Chicago and NYC that examines the effect of the RiSE intervention on DNAm pre- and post-intervention, and its overall influence on inflammatory burden. Salivary DNAm will be measured at baseline and 6 months following the intervention, using the Oragene-DNA kit.
View Article and Find Full Text PDFBias and Accuracy of Glomerular Filtration Rate Estimating Equations in the US: A Systematic Review and Meta-Analysis.
JAMA Netw Open
March 2024
Division of Nephrology, Department of Medicine, Stanford University School of Medicine, Palo Alto, California.
Importance: There is increasing concern that continued use of a glomerular filtration rate (GFR) estimating equation adjusted for a single racial group could exacerbate chronic kidney disease-related disparities and inequalities.
Objective: To assess the performance of GFR estimating equations across varied patient populations.
Data Sources: PubMed, Embase, Web of Science, ClinicalTrials.
Challenging Race-Based Medicine Through Historical Education About the Social Construction of Race.
Health Equity
November 2023
Department of Psychology, University of Georgia, Athans, Georgia, USA.
Background: Scientifically, there is little genetic variation among humans and race has no biological basis. However, medical school preclinical curricula tend to misrepresent race and reify biologically essentialist explanations for disease. The social construct of race is, therefore, used to inform health care providers' treatment decisions.
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