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The influence of orthodontist change on treatment duration and outcomes in patients treated with Clark's twin block appliance followed by non-extraction fixed mechanotherapy - a retrospective cohort study.
BMC Oral Health
December 2024
Section of Dentistry, Department of Surgery, The Aga Khan University Hospital, Stadium Road, P.O Box 3500, Karachi, 74800, Pakistan.
Background: Post-graduate resident turnover in public and teaching hospital orthodontic clinics often leads to challenges in maintaining the same level of efficacy when a care provider changes during orthodontic treatment. This retrospective cohort study aimed to compare the duration and quality of treatment outcomes between two patient groups: the transfer group, who underwent orthodontic care from multiple residents, and the non-transfer group, whose entire treatment was overseen by a single resident.
Methods: Sixty-six patients were enrolled and equally divided into transfer and non-transfer groups.
An In Vivo Study to Compare the Clinical Effectiveness of Clear Retainer Made on a Conventional and a Digitally Fabricated Model Over a Six-Month Period After Debonding.
Cureus
February 2024
Orthodontics and Dentofacial Orthopedics, Sri Guru Ram Das Institute of Dental Sciences and Research, Amritsar, IND.
Background With the advent of 3D printing, many more possibilities have arisen for treatment planning. 3D rapid prototyping has enabled us to see a whole other dimension that has helped us to give the best possible care for our patients. With more and more advancements being made in this subject, it becomes necessary to check the reliability of the equipment and its effectiveness in the management of the problem at hand.
View Article and Find Full Text PDFA Hierarchical Mechanotransduction System: From Macro to Micro.
Adv Sci (Weinh)
March 2024
Department of Endocrinology and Metabolism, Center for Diabetes Metabolism Research, State Key Laboratory of Biotherapy and Cancer Center, West China Medical School, West China Hospital, Sichuan University and Collaborative Innovation Center, Chengdu, Sichuan, 610041, China.
Mechanotransduction is a strictly regulated process whereby mechanical stimuli, including mechanical forces and properties, are sensed and translated into biochemical signals. Increasing data demonstrate that mechanotransduction is crucial for regulating macroscopic and microscopic dynamics and functionalities. However, the actions and mechanisms of mechanotransduction across multiple hierarchies, from molecules, subcellular structures, cells, tissues/organs, to the whole-body level, have not been yet comprehensively documented.
View Article and Find Full Text PDFTransformable nano-antibiotics for mechanotherapy and immune activation against drug-resistant Gram-negative bacteria.
Sci Adv
August 2023
Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, Institute of Analytical Chemistry, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, P. R. China.
The dearth of antibiotic candidates against Gram-negative bacteria and the rise of antibiotic resistance create a global health concern. The challenge lies in the unique Gram-negative bacterial outer membrane that provides the impermeable barrier for antibiotics and sequesters antigen presentation. We designed a transformable nano-antibiotics (TNA) that can transform from nontoxic nanoparticles to bactericidal nanofibrils with reasonable rigidity (Young's modulus, 21.
View Article and Find Full Text PDFDoes Orthodontics Extractions Negatively Affect The Occlusal Bite Force Of An Individual - A Quasi-Experimental Study.
J Ayub Med Coll Abbottabad
November 2022
Jinnah Medical and Dental College, Dow University of Health Sciences Karachi, Pakistan.
Background: Orthodontics is said to be that branch of dentistry which takes into consideration the facial growth, dentition development as well as occlusion. It is also concerned with the prevention as well as the rectification of the occlusal anomalies. The aim of this study was to determine the occlusal bite force (OBF) changes during fixed orthodontic treatment up to a period of 9 month in Class I patients treated with extraction and non-extraction treatment protocol.
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