In September 2020, the surgeon Paulo Macchiarini, who used stem cell technology to enable the transplants of artificial and donor trachea, was charged with aggravated assault in Sweden. In this comment, we argue that the Ethics Council of the Karolinska Institute should have considered issues from philosophy of science when they were brought to their attention, rather than dismiss them as irrelevant to research ethics. We demonstrate how conceptual issues of a philosophy-of-science-kind about clinical research and medical practice should be integral to research ethics.
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http://dx.doi.org/10.1007/s11673-022-10198-4 | DOI Listing |
Zh Nevrol Psikhiatr Im S S Korsakova
December 2024
European University at St. Petersburg, St. Petersburg, Russia.
An important area of V.M. Bekhterev's scientific research, which to this day does not have a productive resolution and remains controversial, was an attempt to combine the science of the human psyche with a speculative philosophy close to pantheistic views about the «universal soul».
View Article and Find Full Text PDFAutism Res
December 2024
Psychiatry and Addictology Department, CIUSSS-NIM Research Center, University of Montreal, Montreal, Quebec, Canada.
Child-directed speech (CDS), which amplifies acoustic and social features of speech during interactions with young children, promotes typical phonetic and language development. In autism, both behavioral and brain data indicate reduced sensitivity to human speech, which predicts absent, decreased, or atypical benefits of exaggerated speech signals such as CDS. This study investigates the impact of exaggerated fundamental frequency (F0) and voice-onset time on the neural processing of speech sounds in 22 Chinese-speaking autistic children aged 2-7 years old with a history of speech delays, compared with 25 typically developing (TD) peers.
View Article and Find Full Text PDFBreast Cancer Res
December 2024
Department of Clinical Research Design and Evaluation, The Samsung Advanced Institute for Health Sciences & Technology (SAIHST), Sungkyunkwan University, 81 Irwon-ro, Gangnam-gu, Seoul, 06351, Republic of Korea.
Background: Depression among breast cancer survivors is a significant concern affecting their long-term survivorship and quality of life. This study investigates the incidence of depression among breast cancer survivors and identifies associated risk factors.
Methods: This retrospective cohort study used data from the Korean National Health Insurance Service database and included 59,340 breast cancer patients without a history of depression who underwent surgery between January 1, 2010, and December 31, 2016.
Pediatr Rheumatol Online J
December 2024
Child Health Evaluative Sciences, Research Institute, The Hospital for Sick Children, 686 Bay Street, Room 06.9715, Toronto, ON, M5G 0A4, Canada.
Background: Juvenile Idiopathic Arthritis (JIA) is a chronic pediatric illness, whereby youth experience physical, emotional and psychosocial challenges that result in reduced health related quality of life (HRQL). Peer mentoring has been shown to improve disease self-management in adults with chronic conditions, with mixed results in younger populations. Building on our pilot work - which supported the feasibility and initial effectiveness of the iPeer2Peer program - the objective of this study was to assess the clinical effectiveness of the program in youth with JIA through a waitlist randomized controlled trial.
View Article and Find Full Text PDFBMC Psychiatry
December 2024
Department of Midwifery, School of Nursing and Midwifery, Mashhad University of Medical Sciences, Mashhad, Iran.
Aim: To explore the perception of the impact of endometriosis on various aspects in affected women with endometriosis.
Method: Data was gathered through in-depth and semi-structured individual interviews using open questions to comprehend women's experiences with endometriosis and their health-promoting lifestyle. The Conventional Qualitative Content Analysis approach was utilized, and sampling continued until data saturation.
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