Human breast milk due to its unique composition and the ability to adapt to the needs of the infant, is referred to as the "gold standard". Exclusive breastfeeding is recommended for the first 6 months of a inflant's life. The composition of breast milk and its metabolites is not constant and varies depending on the influence of various factors. Its analysis allows for rational management of infant nutrition. Intermediate and final metabolites of human milk are formed as a result of various metabolic processes in the mammary gland, and their role and the influence of various factors on them are not fully determined in the context of the proper development of infants. Metabolomic studies can be used to identify intermediate and terminal metabolites in breast milk. The aim of the study was to review the current literature on the variability of human milk metabolome depending on factors such as gestational age, lactation stage and mother's diet. A review of current research shows that the composition of human milk metabolome varies depending on various factors. Better understanding of metabolome of breast milk could be crucial in the future programming of metabolic processes in infants, which is crucial in preventing many diseases and maintaining health.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.32394/rpzh.2022.0214 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Hygienic-sanitary quality of donated human milk in terms of the donor profile and pumping site.
Rev Esc Enferm USP
January 2025
Universidade Federal de São Paulo, Escola Paulista de Enfermagem, Departamento de Enfermagem na Saúde da Mulher, São Paulo, SP, Brazil.
Objective: To analyze the factors associated with the hygienic-sanitary quality of donated human milk in terms of the donor profile and pumping site.
Method: Cross-sectional study with retrospective data collection of records of human milk samples donated to a Human Milk Bank in São Paulo, Brazil, from 2014 to 2019. Characteristics of human milk donors, pumping site, and hygienic-sanitary quality were analyzed based on the Standards of the Brazilian Human Milk Bank Network.
Breast Morphogenesis: From Normal Development to Cancer.
Adv Exp Med Biol
January 2025
Stem Cell Research Unit, Biomedical Center, School of Health Sciences, University of Iceland, Reykjavik, Iceland.
The human breast gland is composed of branching epithelial ducts that culminate in milk-producing units known as terminal duct lobular units (TDLUs). The epithelial compartment comprises an inner layer of luminal epithelial cells (LEP) and an outer layer of contractile myoepithelial cells (MEP). Both LEP and MEP arise from a common stem cell population.
View Article and Find Full Text PDFFactors influencing breast milk donation to a human milk bank in Iran: implications for policymakers and planners.
BMC Nutr
January 2025
Department of Infectious Disease Epidemiology, London School of Hygiene & Tropical Medicine, London, UK.
Background: The World Health Organization (WHO) actively promotes breastfeeding as the optimal source of nourishment for infants and young children. However, not all newborns have access to breast milk, leading to deprivation of its nutritional benefits or incurring financial burdens from alternative feeding options. Establishing Human Milk Banks (HMBs) can help ensure equitable access to donated human milk.
View Article and Find Full Text PDFBreastfeeding Attitudes and Milk Production of Mothers Staying in Single and Double Rooms after Birth: A Cross-Sectional Comparative Study.
Breastfeed Med
January 2025
Midwifery Department, Ege University Faculty of Health Sciences, Izmir, Turkey.
There is limited evidence on whether the interaction of mothers staying in double rooms (DRs) in the hospital after birth affects breastfeeding attitudes and milk production. To compare the breastfeeding attitudes and milk production of mothers staying in a DR in the hospital after birth with mothers staying in a single room (SR). In the study, 181 mothers who gave birth at term were included.
View Article and Find Full Text PDFAntiparasitic activity of the iron-containing milk protein lactoferrin and its potential derivatives against human intestinal and blood parasites.
Front Parasitol
February 2024
Department of Pharmacy Practice and Science, College of Pharmacy, University of Kentucky, Lexington, KY, United States.
An iron-containing milk protein named lactoferrin (Lf) has demonstrated antiparasitic and immunomodulatory properties against a variety of human parasites. This protein has shown its capability to bind and transport iron molecules in the vicinity of the host-pathogen environment. The ability of parasites to sequester the iron molecule and to increase their pathogenicity and survival depends on the availability of iron sources.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!