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New agents for DOAC reversal: a practical management review. | LitMetric

New agents for DOAC reversal: a practical management review.

Br J Cardiol

Consultant Physician and Epidemiologist Department of Haematological Medicine, Guys and St Thomas' NHS Foundation Trust, King's College London, Westminster Bridge Road, London, SE1 7EH.

Published: January 2022

AI Article Synopsis

  • Bleeding is the most frequent and serious issue linked to the use of anticoagulants, necessitating careful management.
  • For severe or life-threatening bleeding, specific antidotes for direct oral anticoagulants (DOACs) are crucial and recommended for effective treatment.
  • The review presents detailed information on these antidotes, including when to use them, how to dose them, and their possible side effects.

Article Abstract

Bleeding is the commonest and most concerning adverse event associated with anticoagulants. Bleeding, depending on the severity, is managed in various ways, and for severe or life-threatening bleeding, specific antidotes are indicated and recommended. This review provides guidance relating to specific direct oral anticoagulant (DOAC) reversal agents, the antidotes. We discuss their indications for use, dosing, and potential side effects.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9196076PMC
http://dx.doi.org/10.5837/bjc.2022.001DOI Listing

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