Bovine astrovirus (BoAstV) is a small non-enveloped virus with a single-stranded positive-sense RNA. In 1978, BoAstV was first found in calf diarrhea fecal samples in the United Kingdom and since then it has been reported in many other countries. It has wide tissue tropism and can infect multiple organs, including the intestine, nerves and respiratory tract. Since BoAstV is prevalent in healthy as well as clinically infected bovines, and is mostly associated with co-infection with other viruses, the pathogenic nature of BoAstV is still unclear. At present, there are no stable passage cell lines available for the study of BoAstV and animal model experiments have not been described. In addition, it has been reported that BoAstV may have the possibility of cross-species transmission. This review summarizes the current state of knowledge about BoAstV, including the epidemiology, evolution analysis, detection methods, pathogenesis and potential cross species transmission, to provide reference for further research of BoAstV.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228355 | PMC |
| http://dx.doi.org/10.3390/v14061217 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Development of a one-step multiplex RT-qPCR method for rapid detection of bovine diarrhea viruses.
Front Cell Infect Microbiol
February 2025
Veterinary Diagnostic Center, Shanghai Animal Disease Control Center, Shanghai, China.
Introduction: Viral calf diarrhea poses a significant challenge to the cattle industry worldwide due to its high morbidity and mortality rates, leading to substantial economic losses. The clinical symptoms associated with various diarrhea pathogens often overlap, complicating accurate diagnosis; thus, there is an urgent need for rapid and precise diagnostic methods to improve prevention and treatment efforts. In this study, we developed a one-step multiplex reverse-transcription quantitative real-time polymerase chain reaction (mRT-qPCR) that enables the simultaneous detection of three key viral pathogens responsible for calf diarrhea: bovine kobuvirus (BKoV), bovine astrovirus (BoAstV), and bovine torovirus (BToV).
View Article and Find Full Text PDFBovine astrovirus and its role in lymphocytic encephalitis in cattle in Ontario, Canada, 1988-2019.
J Vet Diagn Invest
May 2024
Department of Pathobiology, University of Guelph, Guelph, Ontario, Canada.
Article Synopsis
- A study found neurotropic bovine astrovirus (BoAstV) in 19% of examined cattle with idiopathic lymphocytic encephalitis from 1988 to 2019, highlighting a previously undetected infection in cattle aged 4 months and older.
- The majority of positive cases were in younger cattle (1-2 years old) and displayed acute neurologic symptoms shortly before death or euthanasia, with significant inflammation observed in the brain and spinal cord.
- While other potential infectious causes were identified in some cases, 64% of the lymphocytic encephalitis cases remained without a known cause, indicating that BoAstV infections have been present for years but haven't increased in recent occurrences.
High prevalence of Enterovirus E, Bovine Kobuvirus, and Astrovirus revealed by viral metagenomics in fecal samples from cattle in Central Colombia.
Infect Genet Evol
January 2024
Centro de Investigaciones en Microbiología y Biotecnología - UR (CIMBIUR), Facultad de Ciencias Naturales, Universidad del Rosario, Bogotá, Colombia. Electronic address:
Article Synopsis
- Livestock is key for food security and the economy, but viral infections can harm cattle health and pose risks to human and animal health, making virus identification critical for prevention and control.
- The study focused on characterizing viral communities in cattle fecal samples from Ubaté Province, Colombia, using advanced metagenomic sequencing techniques.
- Findings showed a stable viral composition dominated by Picornaviridae family members, with significant discoveries of viruses like Enterovirus E and Bovine Astrovirus, marking the first report of certain veterinary-important viruses in Colombia.
A survey of fecal virome and bacterial community of the diarrhea-affected cattle in northeast China reveals novel disease-associated ecological risk factors.
mSystems
January 2024
Key Laboratory of Bovine Disease Control in Northeast China, Ministry of Agriculture and Rural affairs of the People's Republic of China, Heilongjiang Provincial Key Laboratory of Prevention and Control of Bovine Diseases, College of Animal Science and Veterinary Medicine, Heilongjiang Bayi Agricultural University, Daqing, China.
Limited information on the virome and bacterial community hampers our ability to discern systemic ecological risk factors that cause cattle diarrhea, which has become a pressing issue in the control of disease. A total of 110 viruses, 1,011 bacterial genera, and 322 complete viral genomes were identified from 70 sequencing samples mixed with 1,120 fecal samples from 58 farms in northeast China. For the diarrheic samples, the identified virome and bacterial community varied in terms of composition, abundance, diversity, and geographic distribution in relation to different disease-associated ecological factors; the abundance of identified viruses and bacteria was significantly correlated with the host factors of clinical status, cattle type, and age, and with environmental factors such as aquaculture model and geographical location ( < 0.
View Article and Find Full Text PDFDetection of the dominant pathogens in diarrheal calves of Ningxia, China in 2021-2022.
Front Vet Sci
April 2023
College of Veterinary Medicine, Northwest A&F University, Xianyang, Shaanxi, China.
Introduction: Calf diarrhea is a complex disease that has long been an unsolved problem in the cattle industry. Ningxia is at the forefront of China in the scale of cattle breeding, and calf diarrhea gravely restricts the development of Ningxia's cattle industry.
Methods: From July 2021 to May 2022, we collected diarrhea stool samples from calves aged 1-103 days from 23 farms in five cities in Ningxia, and performed PCR using specific primers for 15 major reported pathogens of calf diarrhea, including bacteria, viruses, and parasites.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!