Network management strategies depend on a timely and accurate knowledge of the network performance measures. Among these, one of the most relevant is the delay of the links, which unfortunately is not easy to measure with accuracy, especially when considering multi-hop paths. This is a classical networking problem, for which several solutions have been proposed. Nonetheless, we argue in this manuscript that there is still some room for improving accuracy and effectiveness in the measurement. This paper proposes a new solution based on the exploitation of the P4 data plane programming language. The basic idea is to handle lightweight probe packets that are forged ad-hoc at the edge of a link and processed at the other edge. Hosts generate the probe packets that are then exploited by the P4 programs in the switches to implement the measure. This approach provides an accurate and reliable measure of the link transit time, also effective in multi-hop links. In this latter case, we show that the measurement is not influenced much by the packet loss when the network is overloaded, thus providing more reliable results with respect to more conventional tools such as the classical ping utility. The manuscript explains the proposed P4 solution; then, it provides a comparison with several other approaches found in the literature, showing that outperform most of them, and finally show the behavior of the proposed methodology when facing a multi hop network path on a congested network to prove its robustness.
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http://dx.doi.org/10.3390/s22124411 | DOI Listing |
Clin Neuroradiol
January 2025
Department of Endocrinology, Diabetology, Metabolic Diseases and Clinical Chemistry (Internal Medicine 1), Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.
Background: Cardiovascular risk management is beneficial, but stringent glycemic control does not prevent the progression of distal sensorimotor polyneuropathy (DSPN). Persistent hyperglycemia-induced alterations and cardiovascular factors may contribute to diabetes-associated nerve damage. This study aimed to evaluate the correlation between skin auto-fluorescence (sAF), an indicator of dermal advanced glycation end-product (AGE) accumulations, cardiovascular risk, and changes in peripheral nerve integrity.
View Article and Find Full Text PDFSci Rep
January 2025
Donders Institute for Brain, Cognition and Behavior, Radboud University, Thomas Van Aquinostraat 4, 6525, Nijmegen, The Netherlands.
Psychopathic traits and antisocial behavior show a well-documented relationship with decreased empathic processing. It has been proposed that a reduced own experience of pain leads to perceiving others' pain as less severe, which potentially facilitates exploitative, aggressive behavior towards others. We evaluated the link between psychopathic traits, experimental pain sensitivity and empathy for pain in a community sample (n = 74).
View Article and Find Full Text PDFBehav Brain Res
January 2025
Department of Psychiatry, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China; Department of Psychiatry and Institute of Neuropsychiatry, Renmin Hospital of Wuhan University, Wuhan 430060, Hubei, PR China; Taikang Center for Life and Medical Sciences, Wuhan University, Wuhan, 430071, China. Electronic address:
Background: The global burden of major depressive disorder (MDD) is rising, with current diagnostic methods hindered by significant subjectivity and low inter-rater reliability. Several studies have implied underlying link between coagulation-related proteins, such as kininogen (KNG) and coagulation factor VIII (FVIII), and depressive symptoms, offering new insights into the exploration of depression biomarkers. This study aims to elucidate the roles of KNG and FVIII in depression, potentially providing a foundational basis for biomarker research in this field.
View Article and Find Full Text PDFJ Expo Sci Environ Epidemiol
January 2025
Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Background: Elemental analysis of teeth allows for exposure assessment during critical windows of development and is increasingly used to link early life exposures and health. The measurement of inorganic elements in teeth is challenging; laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS) is the most widely used technique.
Objective: Both synchrotron x-ray fluorescence (SXRF) and LA-ICP-MS have the capability to measure elemental distributions in teeth with each having distinct advantages and disadvantages.
Br J Radiol
January 2025
Shenzhen University Medical School, Shenzhen University, Shenzhen, Guangdong, 518055, China.
Objective: The purpose of this study was to assess the severity of hemifacial spasm (HFS) through quantitative measures that associated it with neurovascular contact (NVC).
Methods: We enrolled 108 HFS patients (63 severe and 45 mild cases) and implemented a human-in-the-loop approach to develop a quantitative NVC feature package. This process involved using interactive segmentation on three-dimensional volumetric interpolated breath-hold examination (VIBE) MR images to delineate vascular and nerve structures.
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