Eighty patients with operatively proven lumbar disc herniation or lumbar spondylosis were preoperatively evaluated with metrizamide myelography followed by metrizamide-enhanced computed tomography (CT). The x-ray films were reviewed without knowledge of the operative findings, and the patients were subdivided into those with disc extrusions, spondylosis, or recurrent abnormalities. For the group as a whole, CT was correct in 82% and myelography was correct in 77%. Both CT and myelography together were accurate in 91%, a significant improvement (P less than 0.02). The authors conclude that, if both studies are performed, the percentage of cases correctly diagnosed is increased. Therefore, both metrizamide myelography and metrizamide-enhanced CT should be obtained in selected cases. A review of the literature is included.
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http://dx.doi.org/10.1227/00006123-198703000-00004 | DOI Listing |
Vet Radiol Ultrasound
December 2007
Atlantic Veterinary College, University of Prince Edward Island, Charlottetown, PE, Canada.
Standing myelography in the horse has been previously described. In that study, metrizamide was used and significant complications were reported. In recent years, the introduction of less-toxic nonionic contrast media has reduced the incidence of complications.
View Article and Find Full Text PDFNeurocirugia (Astur)
February 2006
Department of Human Physiology and Pharmacology V. Erspamer, University La Sapienza, Rome, Italy.
Lumbosacral nerve root anomalies are a rare group of congenital anatomical anomalies. Various types of anomalies of the lumbosacral nerve roots have been documented in the available international literature. Generally speaking, these anomalies may consist of a bifid, conjoined structure, of a transverse course or of a characteristic anastomized appearance.
View Article and Find Full Text PDFNo To Shinkei
September 2005
Department of Neurosurgery, Orthopedic Surgery, Hiratsuka City Hospital, 1-19-1 Minamihara, Hiratsuka-City, Kanagawa 254-0065, Japan.
Iohexol (Omnipaque) is a non-ionic contrast media for neuroradiology, which causes the neurological complications on rare occasions. A 63-year-old, righthanded female suffered from dysphemia 12 hours after myelography with iohexol via lumbar puncture. The initial cerebral computed tomography scan revealed the generalized contrast media uptake into the cisterns, which was typical to the finding after intrathecal iohexol injection.
View Article and Find Full Text PDFAnn Pharmacother
October 2003
School of Pharmacy, University of Pittsburgh, Pittsburgh, PA 15213-2546, USA.
Objective: To review seizure risk of concomitant medication administration and nonionic, water-soluble radiographic contrast media agents for myelography.
Data Sources: Clinical literature was identified through MEDLINE (1966-May 2003). Key search terms included metrizamide, iohexol, myelogram, myelography, seizure, and contraindications.
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