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A convenient procedure of synthesis of -carbamoyl-protected propargylic amines substituted with a cyclopropyl group from α-amido sulfones and cyclopropylacetylene is described. The reaction is catalyzed by a chiral BINOL-type zinc complex and provides the corresponding products in good yields and enantioselectivities.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9231313 | PMC |
| http://dx.doi.org/10.3390/molecules27123763 | DOI Listing |
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