AI Article Synopsis
- The study focuses on understanding the physiological limitations in patients experiencing dyspnea (shortness of breath) after mild COVID-19.
- Patients who had mild COVID-19 (group A) were compared with those who had moderate/severe COVID-19 (group B) and those with unexplained dyspnea (group C) using various tests like pulmonary function tests and cardiopulmonary exercise tests.
- Results showed that while diffusion capacity was lower in group B compared to group A, the 6-minute walk test was normal for both groups, and group A had higher oxygen uptake, suggesting different underlying mechanisms for dyspnea in mild and more severe cases.
- The study concludes that patients with mild post-COVID dyspnea exhibited normal
Article Abstract
Background: Post mild COVID-19 dyspnea is poorly understood. We assessed physiologic limitations in these patients.
Methods: Patients with post mild COVID-19 dyspnea (group A) were compared (pulmonary function tests, 6-min walk test (6MWT), echocardiography and cardiopulmonary exercise test (CPET)) to post moderate/severe COVID-19 (group B) and to CPET and spirometry of patients with unexplained dyspnea (group C).
Results: The study included 36 patients (13 in A, 9 in B and 14 in C). Diffusion capacity was lower in group B compared to group A (64 ± 8 vs. 85 ± 9% predicted, = 0.014). 6MWT was normal and similar in both patient groups. Oxygen uptake was higher in group A compared to groups B and C (108 ± 14 vs. 92 ± 13 and 91 ± 23% predicted, = 0.013, 0.03, respectively). O pulse was normal in all three groups but significantly higher in the mild group compared to the control group. Breathing reserve was low/borderline in 2/13 patients in the mild group, 2/9 in the moderate/severe group and 3/14 in the control group (NS).
Conclusions: Patients with post mild COVID-19 dyspnea had normal CPET, similar to patients with unexplained dyspnea. Other mechanisms should be investigated and the added value of CPET to patients with post mild COVID-19 dyspnea is questionable.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224561 | PMC |
| http://dx.doi.org/10.3390/jpm12060874 | DOI Listing |
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