AI Article Synopsis
- * Genome-wide studies have identified various heritable risk factors that may not only inform stroke research but also have applications in other fields.
- * The review will cover key studies on the genetics of ischaemic stroke and explore how this genetic data can help uncover biological links, establish disease causality, and identify promising drug targets.
Article Abstract
Ischaemic stroke is a complex disease with some degree of heritability. This means that heritability factors, such as genetics, could be risk factors for ischaemic stroke. The era of genome-wide studies has revealed some of these heritable risk factors, although the data generated by these studies may also be useful in other disciplines. Analysis of these data can be used to understand the biological mechanisms associated with stroke risk and stroke outcome, to determine the causality between stroke and other diseases without the need for expensive clinical trials, or to find potential drug targets with higher success rates than other strategies. In this review we will discuss several of the most relevant studies regarding the genetics of ischaemic stroke and the potential use of the data generated.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9224543 | PMC |
| http://dx.doi.org/10.3390/ijms23126840 | DOI Listing |
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