AI Article Synopsis
- The study aimed to investigate the relationship between patients' self-assessed disease activity in rheumatoid arthritis (RA) and their reported symptoms, despite having low joint counts.
- Patients with RA reported significant pain in joints not included in the typical 28-joint count; this suggests that these excluded areas may still be impacted by RA and could benefit from treatment.
- Most patients in the study experienced fatigue, supporting the idea that even with low joint counts, they can still feel considerable discomfort and may require further evaluation and management.
Article Abstract
Objective: In patients with rheumatoid arthritis (RA) with low 28-joint tender and swollen joint counts but who assessed their disease as active, to evaluate whether activity reflected RA symptoms.
Methods: We carried out a cross-sectional study of patients in BRASS, a cohort of patients with established RA who had 28-joint counts assessed, scored their disease activity, identified their painful joints, and answered questions about other sites of pain and fatigue. Patients and their rheumatologists were asked about the presence of fibromyalgia. We examined whether patients reported pain in joints excluded from the 28-joint joint count (feet, ankles, hips, neck) and pain or symptoms probably unrelated to RA including low back pain, headache and fibromyalgia. Fatigue was not classified. Analyses were descriptive.
Results: Of 272 patients, 49 had tender and swollen joint counts <1 and a patient global assessment score of ≥3/10. 48/49 (95%) reported pain in joints excluded from the 28-joint count. Of these 49, 24 (45%) also had other symptoms especially low back pain. Fatigue was present in all patients. No patient had fibromyalgia.
Conclusion: If joint counts <=1 are scored in 28 joints, patient global assessments of ≥3/10 often occur when there is pain in uncounted joints, joints that may respond to RA treatment.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9226990 | PMC |
| http://dx.doi.org/10.1136/rmdopen-2022-002346 | DOI Listing |
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