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Investigating the effect of localized heat treatment and bioinspired structure on the crashworthiness of bumper subsystem.
Heliyon
January 2025
Faculty of Mechanical and Industrial Engineering, Bahir Dar Institute of Technology, Bahir Dar University, Bahir Dar, Ethiopia.
Particularly when they occur at high speeds, vehicle accidents represent a serious threat to human beings and due to this fact vehicle accident is considered as worlds high priority risk. Several research have been done to enhance the crashworthiness of bumper subsystems. With an emphasis on the major crash management system components which are also known as crash box and bumper beam, this study explores ways to improve the crashworthiness of vehicles.
View Article and Find Full Text PDFMiniature Mass Spectrometry for Point-of-Care Testing the GPIIb/IIIa Inhibitor Tirofiban during Perioperative Period of Percutaneous Coronary Intervention.
ACS Omega
December 2024
Panvascular Diseases Research Center, The Quzhou Affiliated Hospital of Wenzhou Medical University, Quzhou People's Hospital, Quzhou 324000, China.
Article Synopsis
- The study developed a portable mass spectrometry technique for accurately measuring tirofiban drug concentrations in blood to enhance patient safety and treatment efficacy.
- The method identified a significant parent ion peak for tirofiban and optimized various parameters, achieving a limit of detection (LOD) and limit of quantification (LOQ) of 10.1 and 33.7 μg·L, respectively.
- Although the technique faced some challenges from blood sample matrix effects, it successfully detected tirofiban in 10 out of 12 clinical samples, demonstrating the need for further optimization and validation to boost sensitivity and stability.
Higher precision constraints on the tau in LHC photon-initiated production: a full account of hadron dissociation and soft survival effects.
Eur Phys J C Part Fields
December 2024
Department of Physics and Astronomy, University College London, London, WC1E 6BT UK.
Article Synopsis
- This study is the first to calculate how photon-initiated pair production is affected by non-zero anomalous magnetic and electric dipole moments of leptons, considering their interplay with survival factors and potential dissociation of hadron beams.
- The authors found that the impact of these factors is generally minor (on the percent level) in current experimental analyses but will become more significant as measurement precision improves.
- To assist future research, the calculations have been integrated into the SuperChic Monte Carlo generator, allowing simulation of this process with adjustable parameters without additional reruns.
Energy-Resolved Mass Spectrometry and Mid-Infrared Spectroscopy for Purity Assessment of a Synthetic Peptide Cyclised by Intramolecular Huisgen Click Chemistry.
Methods Protoc
December 2024
Univ Brest, CEMCA, CNRS, UMR 6521, 29238 Brest, France.
Cyclic peptides have higher stability and better properties as therapeutic agents than their linear peptide analogues. Consequently, intramolecular click chemistry is becoming an increasingly popular method for the synthesis of cyclic peptides from their isomeric linear peptides. However, assessing the purity of these cyclic peptides by mass spectrometry is a significant challenge, as the linear and cyclic peptides have identical masses.
View Article and Find Full Text PDFThe Puck Stops Here: Head and Neck Ice Hockey Lacerations in Adults.
Laryngoscope
December 2024
Department of Otolaryngology, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, Buffalo, New York, U.S.A.
Objective: The goal of this study was to describe lacerations of the head and neck sustained among ice hockey players in the US.
Methods: Data on adult (20-65 years) ice hockey injuries were collected from the 2003-2022 National Electronic Injury Surveillance System (NEISS) database. Injuries of the head, neck, face, mouth, and ears were included, while those sustained as a spectator, coach, or on a non-ice surface were excluded.
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