Lesniowski-Crohn's disease (CD) is a type of chronic inflammatory bowel disease (IBD) of uncertain etiology. Initially, pharmacological management is undertaken; however, surgical intervention is necessary to improve life quality and relieve symptoms in most cases. Here changes are reported in blood metabolome that occurred three days after the ileo-colic region resection in the case of seven patients. Alterations are observed in levels of metabolites associated with multiple mitochondrial pathways, based on the Metabolite Set Enrichment Analysis, reflecting a high energy demand in the post-operative period. As most of these metabolites are also essential nutrients supplied from foods, we believe that our results might contribute to the discussion on perioperative nutrition's role in enhanced recovery.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9228040 | PMC |
http://dx.doi.org/10.3390/metabo12060529 | DOI Listing |
Metabolites
June 2022
Department of Bromatology, Faculty of Pharmacy, Medical University of Warsaw, Stefana Banacha 1, 02-097 Warsaw, Poland.
Lesniowski-Crohn's disease (CD) is a type of chronic inflammatory bowel disease (IBD) of uncertain etiology. Initially, pharmacological management is undertaken; however, surgical intervention is necessary to improve life quality and relieve symptoms in most cases. Here changes are reported in blood metabolome that occurred three days after the ileo-colic region resection in the case of seven patients.
View Article and Find Full Text PDFDis Markers
October 2018
Department of Clinical Chemistry and Laboratory Diagnostics, School of Pharmacy and Division of Laboratory Medicine in Sosnowiec, Medical University of Silesia in Katowice, Jedności 8, 41-200 Sosnowiec, Poland.
The nonspecific inflammatory bowel diseases (IBD) represent a heterogeneous group of chronic inflammatory disorders of the gastrointestinal tract, and Leśniowski-Crohn's disease (CD) and ulcerative colitis (UC) are among the two major clinical forms. Despite the great progress in understanding the pathogenesis of these diseases, their etiology remains unclear. Genetic, immune, and environmental factors are thought to play a key role.
View Article and Find Full Text PDFPol Przegl Chir
February 2018
Department of General and Oncological Surgery, Specialist Hospital in Wejherowo, Poland; Head: Mieczysław Witzling MD.
Yersiniosis is zoonotic disease caused by infection with Yersinia enterocolictica. The variety of clinical signs and the similarity to other diseases causes major diagnostics and therapeutics difficulties. The authors present a case of Yersinia enterocolitica infection in a 38-year-old patient, mimicking Leśniowski Crohn's disease.
View Article and Find Full Text PDFStud Health Technol Inform
December 2016
Faculty of Computer Science, Electronics and Telecommunications, AGH University of Science and Technology, Cracow, Poland.
Medical nutrition therapy has a pivotal role in the management of chronic gastrointestinal disorders, like chronic pancreatitis, inflammatory bowel diseases (Leśniowski-Crohn's disease and ulcerative colitis) or irritable bowel syndrome. The aim of this study is to develop, deploy and evaluate an interactive application for Windows and Android operating systems, which could serve as a digital diet diary and as an analysis and a prediction tool both for the patient and the doctor. The software is gathering details about patients' diet and associated fettle in order to estimate fettle change after future meals, specifically for an individual patient.
View Article and Find Full Text PDFOrtop Traumatol Rehabil
September 2011
Orthopaedic Unit, Santa Maria del Prato Hospital, Feltre, Italy.
Background: Inflammatory bowel disease (IBD) is a group of inflammatory conditions of the gastrointestinal tract. The major types of IBD are Lesniowski-Crohn's disease (L-CD) and ulcerative colitis (UC). Inflammatory bowel disease (IBD) sometimes presents with arthritic manifestations.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!