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Outcomes of Tympanic Membrane Regenerative Surgery Using Gelatin Sponge, Recombinant Basic Fibroblast Growth Factor, and Fibrin Glue.
Cureus
December 2024
Otolaryngology, Yokosuka Kyosai Hospital, Yokosuka, JPN.
Objective We evaluated the outcomes of tympanic membrane regenerative treatment using gelatin sponge, recombinant basic fibroblast growth factor (bFGF), and fibrin glue at Yokosuka Kyosai Hospital. Methodology We enrolled a total of 42 patients with tympanic membrane perforations (TMPs) (44 ears; right:left = 21:23) that were treated using gelatin sponge, recombinant bFGF, and fibrin glue between July 2020 and December 2023 at Yokosuka Kyosai Hospital. TMP closure rates, improvement of hearing level, and complications were retrospectively included in the evaluation items.
View Article and Find Full Text PDFSimulation and quantitative evaluation of three surgical techniques of endoscopic enucleation of prostate on a realistic phantom model.
World J Urol
December 2024
Department of Urology, University of Freiburg Medical Center, Freiburg, Germany.
Objective: To evaluate the impact of three different AEEP techniques on the training performance of novices using a realistic hydrogel prostate phantom model.
Material And Methods: The experimental setup utilized realistic prostate phantom model provided by the Max Planck Institute for Intelligent Systems, Germany. For the enucleation, we utilized a new solid-state pulsed thulium laser (Thulio®, Dornier MedTech, Weßling, Germany).
Misdiagnosis of a fungus ball in the middle ear as chronic suppurative otitis media.
J Infect Dev Ctries
November 2024
Department of Otolaryngology, Peking University Shenzhen Hospital, Shenzhen, 518036, China.
Background: Middle ear infections caused by fungi are commonly identified through laboratory tests like fungal smears, culture, and DNA detection. There are two types of ear infections caused by fungi: middle ear fungal infections and fungal otitis media. Both fungal otitis media and fungus balls in the middle ear are increasingly rare.
View Article and Find Full Text PDFAcute kappa opioid receptor blocking disrupts the pro-cognitive effect of cannabidiol in neuropathic rats.
Neuropharmacology
December 2024
Department of Experimental Medicine, Division of Pharmacology, Università della Campania "L. Vanvitelli", Naples, Italy.
Cannabidiol has been shown to ameliorate neuropathic pain and its affective components. Previous studies highlighted the pharmacological interaction between the CBD and opioid system, particularly the MOR, but the understanding of the interaction between CBD and kappa opioid receptor (KOR), physiologically stimulated by the endogenous opioid dynorphin, remains elusive. We assessed the pharmacological interactions between CBD and nor-BNI, a selective KOR antagonist in a rat neuropathic pain model.
View Article and Find Full Text PDFMicroscopic Analysis and Evaluation of Thermal Elevation and Wear of Drills for Implant Site Preparation: An In Vitro Study.
Materials (Basel)
November 2024
Department of Life, Health and Environmental Sciences, University of L'Aquila, 67100 L'Aquila, Italy.
Drilling for implant site preparation generates heat, which can cause bone necrosis if temperatures exceed 47 °C for over a minute. Factors influencing heat include drill size, speed, pressure, irrigation, and tool wear. Frequent drill replacement is essential, as wear from repeated use and sterilization affects performance.
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