AI Article Synopsis

  • The study investigates how well modified Medical Research Council (mMRC) and COPD assessment test (CAT) scores align in evaluating symptoms of chronic obstructive pulmonary disease (COPD) patients.
  • It included 228 stable COPD patients, revealing a strong correlation between CAT and mMRC scores, but identified discrepancies in symptom assessment for 53 patients where scores did not match.
  • The findings suggest that while high scores may indicate severe symptoms, both mMRC and CAT should be used together for accurate classification to avoid misdiagnosing symptom levels.

Article Abstract

Objective: In this study, we aimed to investigate the compatibility of modified Medical Research Council (mMRC) and COPD assessment test (CAT) scores of chronic obstructive pulmonary disease (COPD) patients in terms of evaluation of their symptom status.

Methods: The study was planned as a single-center, cross-sectional study. Statistically four separate receiver operating characteristic (ROC) curves of CAT scoring were generated for mMRC scores of 1 to 4.

Results: Two hundred twenty eight patients with stable COPD, mean age 64.2±8.2 and 88.6% male were included. A strong positive correlation was detected between CAT and mMRC (r=0.60, p<0.001). However, it was observed that 32 patients had mMRC<2 but CAT≥10, while 21 patients had CAT<10 but mMRC≥2. Thus, in 53 patients CAT and mMRC scores were not identical in terms of assessed symptom status. According to the ROC analysis, the mMRC scores of 1 to 4 were most compatible with the CAT scores of 10, 10, 15, and 20, respectively.

Conclusions: Expanding current data represents that CAT score of 10 could be more compatible with mMRC score of 1. Moreover we think although a high mMRC or CAT score may be sufficient to assign patients to high symptom groups, it is needed to evaluate mMRC and CAT together to assign a patient to a low symptom group. In this way misclassification of the patients with high symptoms due to insufficient symptom evaluation as if they have low symptoms can be prevented.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9234363PMC
http://dx.doi.org/10.4274/MMJ.galenos.2022.06787DOI Listing

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