Clinical rebound of COVID-19 after nirmatrelvir/ritonavir treatment has been reported. We performed clinical, virologic, and immune measurements in seven patients with symptomatic rebound, six after nirmatrelvir/ritonavir treatment and one without previous treatment. There was no evidence of severe disease or impaired antibody and T-cell responses in people with rebound symptoms.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9216730PMC
http://dx.doi.org/10.1101/2022.06.16.22276392DOI Listing

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