Case Report: Various Clinical Manifestations Caused by Varicella-Zoster Virus in a Family.

Front Pediatr

Laboratory of Dermatology, Beijing Pediatric Research Institute, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China.

Published: June 2022

A family cluster of varicella-zoster virus (VZV) infections was reported. Four family members (two children and their parents) continuously develop varicella after the grandmother's herpes zoster. The unvaccinated 16-month-old infant and his mother developed primary varicella with atypical clinical presentation; however, his 28-year-old father presented with a typical generalized vesicular rash. His vaccinated 4-year-old sister was clinically mild, which could be defined as a breakthrough varicella case. They infected the same virus strain but presented various clinical forms.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9207272PMC
http://dx.doi.org/10.3389/fped.2022.876250DOI Listing

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