Per-acetylated epigallocatechin-3-gallate (AcEGCG), a fully acetylated derivative of EGCG, a more potent agent for protection of melanocytes from oxidative damage. We present two patients with vitiligo treated with AcEGCG 0.5% cream, who demonstrated skin repigmentation and control of depigmentation progression.
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http://dx.doi.org/10.1111/ced.15211 | DOI Listing |
J Clin Med
January 2025
Department of Dermatology, Miguel Servet University Hospital IIS Aragon, 50009 Zaragoza, Spain.
Vitiligo is a pigmentation disorder that impacts approximately 0.5% to 2% of the global population. Growing interest surrounds the comorbidities associated with vitiligo.
View Article and Find Full Text PDFMedicina (Kaunas)
January 2025
Unit of Dermatology and Cosmetology, IRCCS Ospedale San Raffaele, 20132 Milan, Italy.
: Janus kinase inhibitors (JAKi) have significantly advanced the treatment of various dermatological conditions by modulating the JAK-STAT signalling pathway. While these inhibitors have proven effective, they also pose challenges due to associated increase in serum lipid levels and relative potential cardiovascular risks. This perspective work aims to discuss the implications of these lipid alterations proposing management strategies for patients with dermatological disorders under JAKi treatments.
View Article and Find Full Text PDFGeorgian Med News
November 2024
2Department of Pharmacology, College of Medicine, University of Baghdad, Iraq.
Background: Vitamin D deficiency promotes initiation and sustainment of numerous medical disorders, including cancer, diabetes mellitus, autoimmune disorders, and cardiovascular diseases. The expression of vitamin D receptors by melanocytes suggests a role for it in controlling their physiology.
Aim: Therefore, the aim of this study was to compare serum vitamin D levels in patients with vitiligo and normal healthy individuals.
Indian Dermatol Online J
December 2024
Department of Pathology, All India Institute of Medical Sciences, New Delhi, India.
Introduction: Acquired inflammatory Blaschko-linear dermatoses have not been studied extensively. Descriptive studies on segmental vitiligo have yielded insights helpful in counseling patients. Similar insights are expected from studies on other acquired inflammatory Blaschko-linear diseases.
View Article and Find Full Text PDFIndian Dermatol Online J
December 2024
Department of Experimental and Clinical Medicine, DISM, Institute of Dermatology Udine, Udine, Italy.
Introduction: Ultraviolet-induced fluorescence dermoscopy (UVF dermoscopy) is a novel diagnostic technique for identifying and diagnosing numerous skin tumors, inflammatory dermatoses, and infectious diseases. The ultraviolet (UV) band has a wavelength ranging from 10 to 400 nm. When intense UV radiation with shorter wavelengths strikes a target chromophore, visible light (VL) with a longer wavelength and lower energy is produced in the skin.
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