Pervious pavement system (PPS) is a suitable alternative technique for mitigating urban flooding and urban heat island (UHI) simultaneously. However, existing literature has revealed that PPSs cannot achieve the expected permeability and evaporation. To overcome this gap, this study presents an elaborate review of problems associated with PPSs and highlights its benefits to stormwater management and UHI mitigation. We determined key parameters of PPSs that could influence urban flooding and UHI mitigation, including hydrological properties, thermal physical properties, structure design, and clogging resistance. We identified the co-benefits approach of PPS towards performance synergism on stormwater management and UHI mitigation from quality controlled design and fabrication, periodic maintenance, and effective evaluation system based on practice environments. The results indicate that existing studies of PPSs primarily focus on permeability, while little emphasis is given to the evaporative cooling performance, leading to a biased development with a loss of test standards and regulations that cannot control the cooling potential of the system. The performance synergism of permeability and evaporative cooling in PPS should be studied further, while considering quality control of the materials and in-situ practice design. Parameter controls (with commonly used standards) during fabrication, periodic maintenance (during operation), and pre- and post-evaluation processes of PPSs should work collectively to achieve optimal benefits and reduced costs.
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http://dx.doi.org/10.1016/j.watres.2022.118755 | DOI Listing |
Travel Med Infect Dis
January 2025
General Directorate of Welfare, Regione Lombardia, Milano, Italy.
Introduction: Here we reported the virological, entomological and epidemiological characteristics of the large autochthonous outbreak of dengue (DENV) occurred in a small village of the Lombardy region (Northern Italy) during summer 2023.
Methods: After the diagnosis of the first autochthonous case on 18 August 2023, public health measures, including epidemiological investigation and vector control measures, were carried out. A serological screening for DENV antibodies detection was offered to the population.
Int J Biol Macromol
January 2025
Virus Research Laboratory, ICMR-National Institute of Cholera and Enteric Disease, Kolkata 700010, India. Electronic address:
Human cytomegalovirus (HCMV) is a common herpesvirus that can severely affect transplant recipients, those with AIDS, and newborns. Existing synthetic medications face limitations, including toxicity, processing issues, and viral resistance. As part of this study, the efficacy of the extracellular enzyme laccase isolated from a widely available mushroom (Pleurotus pulmonarius) was compared to that of ganciclovir, a common antiviral, used against HCMV.
View Article and Find Full Text PDFJ Chem Theory Comput
January 2025
Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences, 160 00 Prague, Czech Republic.
Machine learning (ML) methods offer a promising route to the construction of universal molecular potentials with high accuracy and low computational cost. It is becoming evident that integrating physical principles into these models, or utilizing them in a Δ-ML scheme, significantly enhances their robustness and transferability. This paper introduces PM6-ML, a Δ-ML method that synergizes the semiempirical quantum-mechanical (SQM) method PM6 with a state-of-the-art ML potential applied as a universal correction.
View Article and Find Full Text PDFJ Enzyme Inhib Med Chem
December 2025
Department of Organic Chemistry, Medical University of Lublin, Lublin, Poland.
The ever-increasing drug-resistant tuberculosis (TB) has invigorated the focus on the discovery and development of novel therapeutic agents and treatment options. Thiazolidinone-based compounds have shown good antitubercular properties . Here, we report the design and synthesis of a number of new derivatives inspired by the structure of thiazolidine-2,4-dione (TZD).
View Article and Find Full Text PDFSci Rep
January 2025
Key Laboratory of Semi-Arid Climate Change, College of Atmospheric Sciences, Ministry of Education, Lanzhou University, Lanzhou, 730000, China.
The impact of O on the respiratory system is a significant global problem. Nevertheless, there is insufficient information about its impact on respiratory disorders in northeast China. In this study, we used a generalized additive model (GAM) to determine the correlation between O concentrations and respiratory deaths based on the daily meteorological data, pollutant concentrations, and respiratory deaths from 2014 to 2016 in Shenyang, a typical city in northeast China.
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