Introduction: Traditional methods of summarizing burden of disease have limitations in terms of identifying communities within a population that are in need of prevention and intervention resources. This paper proposes a new method of burden assessment for use in guiding these decisions.
Methods: This new method for assessing burden utilizes the sum of population-weighted age-specific z-scores. This new Z-Score Burden Metric was applied to firearm-related deaths in North Carolina counties using 2010‒2017 North Carolina Violent Death Reporting System data. The Z-Score Burden Metric consists of 4 measures describing various aspects of burden. The Z-Score Burden Metric Overall Burden Measure was compared with 2 traditional measures (unadjusted and age-adjusted death rates) for each county to assess similarities and differences in the relative burden of firearm-related death.
Results: Of all 100 North Carolina counties, 73 met inclusion criteria (≥5 actual and expected deaths during the study period in each age strata). Ranking by the Overall Burden Measure produced an ordering of counties different from that of ranking by traditional measures. A total of 8 counties (11.0%) differed in burden rank by at least 10% when comparing the Overall Burden Measure with age-adjusted and unadjusted rates. All the counties with large differences between the measures were substantially burdened by firearm-related death.
Conclusions: The use of the Z-Score Burden Metric provides an alternative way of measuring realized community burden of injury while still facilitating comparisons between communities with different age distributions. This method can be used for any injury or disease outcome and may help to prioritize the allocation of resources to communities suffering high burdens of injury and disease.
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http://dx.doi.org/10.1016/j.amepre.2022.03.029 | DOI Listing |
Nutrients
January 2025
Office of Minority Health and Health Disparities Research, Georgetown Lombardi Comprehensive Cancer Center, Georgetown University, 1010 New Jersey Ave. SE, Washington, DC 20003, USA.
Background/objectives: Nutrient-poor diet quality is a major driver of the global burden of metabolic syndrome (MetS). The US ranks among the lowest in diet quality and has the highest rate of immigration, which may present unique challenges for non-US-native populations who experience changes in access to health-promoting resources. This study examined associations among MetS, nativity status, diet quality, and interaction effects of race-ethnicity among Hispanic, Asian, Black, and White US-native and non-US-native adults.
View Article and Find Full Text PDFJ Environ Sci (China)
July 2025
State Key Laboratory of Environmental and Biological Analysis, Department of Chemistry, Hong Kong Baptist University, Hong Kong, China. Electronic address:
N-(1,3-dimethylbutyl)-N'-phenyl-p-phenylenediamine quinone (6PPDQ) and its parent 6PPD are ubiquitous in the environment and may induce multi-endpoint toxicity. Electronic waste (e-waste) dismantling is an under-recognized source of 6PPD and 6PPDQ emissions, and there is a lack of epidemiological investigations into their presence and health effects in local populations. This study aimed to determine the urinary concentrations of 6PPD and 6PPDQ in children aged 2-7 years from e-waste dismantling areas and evaluate their potential risk to physical growth.
View Article and Find Full Text PDFBMJ Open
January 2025
Pharmaceutics and Social Pharmacy, Addis Ababa University College of Health Sciences, Addis Ababa, Ethiopia.
Objective: This study analysed the spatial and temporal patterns of cervical cancer incidence in Addis Ababa from 2012 to 2021.
Design: An ecological study was conducted from 1 September to 30 November 2023 to examine the spatiotemporal trends of cervical cancer incidence.
Setting: The research was conducted in Addis Ababa, the capital city of Ethiopia.
Ready-to-use supplemental foods (RUSF) are energy-dense meals formulated to prevent and treat moderate and severe childhood acute malnutrition (MAM and SAM) in high-risk settings. Although lifesaving, the degree and durability of weight recovery with RUSF is unpredictable. We examined whether environmental enteric dysfunction (EED) and gut microbiota perturbations are risk factors for RUSF failure in a birth cohort of 416 rural Pakistani children followed for growth, common childhood illnesses, and biomarkers from blood, urine, and stool.
View Article and Find Full Text PDFLancet Glob Health
January 2025
Action Against Hunger, New York, NY, USA; Tufts University, Boston, MA, USA.
Background: Community-based management of acute malnutrition is an effective treatment model for severe acute malnutrition. However, sparse evidence exists on post-discharge outcomes and the sustainability of recovery. This study aimed to evaluate the risk and determinants of relapse following severe acute malnutrition recovery in high-burden settings.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!