We evaluated the construct validity of the Genetics and Genomics Nursing Practice Survey by investigating the factoral structure, while attempting to account for varied response structures of the items. Exploratory factor analyses provided insights into item loadings. Confirmatory factor analyses and a version of common methods bias analyses evaluated construct validity while considering the instrument's structural limitations. Structural equation models provided information regarding model fit. The 7-factor model fit these data slightly better (AIC ≈ 169,405; RMSEA = .052) than did the 5-factor model (AIC ≈ 183,599; RMSEA = .063). Neither the CFI or TLI met commonly-accepted thresholds for adequate model fits. The response format of the GGNPS created challenges in evaluating the instrument for construct validity. Nonetheless, these results support the theory-based construct validity of the GGNPS.
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http://dx.doi.org/10.1891/JNM-2021-0007 | DOI Listing |
Comb Chem High Throughput Screen
January 2025
Thoracic and Abdominal Radiotherapy Department I, Meizhou People's Hospital, Meizhou 514031, Guangdong, China.
Background: TSPOAP1 antisense RNA 1 (TSPOAP1-AS1) is a long non-coding RNA (lncRNA) that has received widespread attention in oncology research in recent years. Its role and mechanism in some cancers have gradually been revealed. However, it is not clear what role TSPOAP1-AS1 plays in cervical cancer (CESC).
View Article and Find Full Text PDFCurr Med Imaging
January 2025
Department of Radiology, Jiangxi Provincial People's Hospital, The First Affiliated Hospital of Nanchang Medical College, Nanchang, China.
Objective: The aim of this study was to develop and validate predictive models for perineural invasion (PNI) in gastric cancer (GC) using clinical factors and radiomics features derived from contrast-enhanced computed tomography (CE-CT) scans and to compare the performance of these models.
Methods: This study included 205 GC patients, who were randomly divided into a training set (n=143) and a validation set (n=62) in a 7:3 ratio. Optimal radiomics features were selected using the least absolute shrinkage and selection operator (LASSO) algorithm.
Small
January 2025
Department of Surgical Oncology and General Surgery Key Laboratory of Precision Diagnosis and Treatment of Gastrointestinal Tumors, Ministry of Education The First Affiliated Hospital of China Medical University, Shenyang, 110001, China.
Current in vitro models for gastric cancer research, such as 2D cell cultures and organoid systems, often fail to replicate the complex extracellular matrix (ECM) found in vivo. For the first time, this study utilizes a gelatin methacryloyl (GelMA) hydrogel, a biomimetic ECM-like material, in 3D bioprinting to construct a physiologically relevant gastric cancer model. GelMA's tunable mechanical properties allow for the precise manipulation of cellular behavior within physiological ranges.
View Article and Find Full Text PDFSmall
January 2025
MOE Key Laboratory for Nonequilibrium Synthesis and Modulation of Condensed Matter, Shaanxi Province Key Laboratory of Advanced Materials and Mesoscopic Physics, School of Physics, Xi'an Jiaotong University, Xi'an, 710049, P. R. China.
Owing to the nanoscale thickness, excellent mechanical and chemical stabilities, 2D materials including graphene and hexagonal boron nitride have emerged as promising artificial solid electrolyte interphase (SEI) candidates for lithium metal batteries. However, whether the implementation of 2D materials is beneficial to electrochemical performance remains controversial, and the key to confining the electroplated Li beneath the 2D materials remains elusive. Here, a nanocrystalline graphene (NG) film is synthesized on high-carbon Cu and the Li plating/stripping behavior on Cu grown with different 2D materials is investigated.
View Article and Find Full Text PDFIntegr Cancer Ther
January 2025
Department of Physiotherapy, School of Life Course and Population Sciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Background: Adherence in rehabilitation services includes attending appointments, regularly performing prescribed exercises, and correct exercise execution. The Exercise Adherence Rating Scale (EARS) has been adapted into several languages, but there is lack of a standardized tool for various Indian languages and cultural contexts, particularly for use with cancer survivors. With the anticipated 57.
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