Introduction And Importance: Mucormycosis is rare type of infection yet, it is common in patient with Diabetes Mellitus and immune deficiencies. Mucormycosis mostly target the rhino-orbito-cerebral region, hence the common presenting symptoms are nasal symptoms followed by orbito-cerebral symptoms.
Case Presentation: Here, we present a diabetic lady with unusual presentation of mucormycosis. This old lady present with long history of left dull ear pain and decrease in hearing, nasopharyngeal exam revealed a mild bulging in the fossa of Rosenmuller region. The mild bulging reported as left nasopharyngeal heterogonous soft tissue mass extending to the left external auditory canal and skull base by CT scan. Excisional biopsy was taken and found to be nasopharyngeal mucormycosis CONCLUSION: Mucormycosis is a fatal infection which require early diagnosis and emergent intervention.
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http://dx.doi.org/10.1016/j.ijscr.2022.107297 | DOI Listing |
JAMA
May 2024
Department of Medicine, Section of Infectious Diseases, Yale School of Medicine, New Haven, Connecticut.
J Med Virol
April 2024
Department of Medicine, AIIMS, New Delhi, Delhi, India.
Coronavirus disease 2019 (COVID-19) associated mucormycosis (CAM) was reported predominantly from India during the second wave of COVID-19 and has a high mortality rate. The present study aims to understand the fungal community composition of the nasopharyngeal region of CAM-infected individuals and compare it with severe COVID-19 patients and healthy controls. The fungal community composition was decoded by analyzing the sequence homology of the internal transcribed spacer-2-(ITS-2) region of metagenomic DNA extracted from the upper respiratory samples.
View Article and Find Full Text PDFInt J Mol Sci
December 2023
Institute of Immunology, RWTH Aachen University Hospital, Pauwelsstraße 30, 52074 Aachen, Germany.
Invasive fungal (IF) diseases are a leading global cause of mortality, particularly among immunocompromised individuals. The SARS-CoV-2 pandemic further exacerbated this scenario, intensifying comorbid IF infections such as mucormycoses of the nasopharynx. In the work reported here, it is shown that zygomycetes, significant contributors to mycoses, are sensitive to the natural product allicin.
View Article and Find Full Text PDFBMC Infect Dis
April 2023
Department of Neurology, Ganzhou People's Hospital, Jiangxi, 341000, China.
Background: Rhizopus delemar is an invasive fungal pathogen that can cause fatal mucormycosis in immunodeficient individuals. Encephalitis caused by R. delemar is rare and difficult to diagnose early.
View Article and Find Full Text PDFCOVID-19 is a serious global infectious disease impairing the quality of life of people across the world. SARS-CoV-2 may reside in nasopharyngeal and salivary secretions of COVID-19-infected patients and spreads mainly through respiratory droplets and fomites. It has presented a challenge to dentistry, as many dental procedures generate aerosols that could lead to cross-contamination.
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