Purpose: To present a new restorative technique for the restoration of teeth with deep subgingival hard tissue defects extending down to the osseous crest without additional surgical or orthodontic interventions by combining mineral trioxide aggregate (MTA) and composite material.
Materials And Methods: The MTA matrix technique starts by deeply inserting a metal matrix as far down to the bone level as possible. The matrix should then be fixated with a matrix holder in its end position. If the matrix band does not seal tightly in the deepest area of the cavity, small portions of MTA are carefully applied to the lower end of the inner side of the matrix band. The MTA acts as a barrier for fluid control. Additional haemostasis is not necessary. Subsequently, the tooth is restored with an etch-and-rinse adhesive and composite resin. The clinical effects were observed in a case series of three patients over a period of 3 to 4.5 years.
Results: Excellent outcomes were observed clinically and radiologically. Teeth restored with the MTA matrix technique showed no failures due to the materials used or due to secondary caries or periodontal inflammation after an observation period of 3 to 4.5 years. Probing depths ranged from 2 to 4 mm without bleeding on probing, including the subgingivally restored areas.
Conclusion: Although only a few casuistic observations are available to date, by using the MTA matrix technique, successful restoration of teeth with subgingival defects down to the alveolar bone crest seems possible without the need of additional surgical or orthodontic measures. Further clinical studies are necessary to confirm the feasibility of this technique.
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http://dx.doi.org/10.3290/j.jad.b3146843 | DOI Listing |
Cureus
December 2024
Department of Conservative Dentistry and Endodontics, School of Dental Science, Krishna Vishwa Vidyapeeth (Deemed To Be University), Karad, IND.
Apexification is a crucial procedure for achieving apical healing in non-vital teeth with open apices. Traditionally, calcium hydroxide has been used for this purpose, but it has significant drawbacks, including prolonged treatment duration, increased risk of root fracture, and the potential for porous barrier formation. Mineral trioxide aggregate (MTA) has emerged as a superior alternative due to its biocompatibility, faster setting time, and better sealing properties.
View Article and Find Full Text PDFEur Endod J
December 2024
Department of Neurosciences, Reproductive and Odontostomatological Sciences, University of Naples Federico II, Naples, Italy.
Objective: To evaluate the effect of a newly developed MTA-based material and two antibacterial-enhanced MTAs as pulp capping materials in immature permanent dental elements underwent full pulpotomy.
Methods: The present animal study included 20 Wistar albino rats that, after full pulpotomy, were randomly divided into 4 groups receiving different MTA formulations as pulp capping materials: conventional MTA, Tricalcium aluminate (TCA)- free MTA, and MTA enhanced with metronidazole or doxycycline. Histopathological assessments were carried out at 7- and 28-days post-treatment to evaluate dentinal bridge formation, inflammatory reactions, pulp tissue necrosis and internal resorption.
Stem Cell Res Ther
December 2024
Institute for Cell Biology (Cancer Research), University Hospital Essen, University of Duisburg-Essen, Essen, Germany.
Background: Organoids, as near-physiological 3D culture systems, offer new opportunities to study the pathogenesis of various organs in mimicking the cellular complexity and functionality of human organs.
Method: Here we used a quite simple and very practicable method to successfully generate induced pluripotent stem cell (iPSC)-derived human lung organoids (LuOrg) in a matrix-free manner as an alternative to the widely used preclinical mouse models in order to investigate normal lung damage in detail and as close as possible to the patient. We performed detailed morphological and molecular analyses, including bulk and single cell RNA sequencing, of generated lung organoids and evaluated the quality and robustness of our model as a potential in vitro platform for lung diseases, namely radiation-induced lung injury.
Nutrients
November 2024
MTA-DE Lendület Vascular Pathophysiology Research Group, Research Centre for Molecular Medicine, Faculty of Medicine, University of Debrecen, 4032 Debrecen, Hungary.
Zinc is the second most abundant trace element in the human body, stored mainly in the bones. Zinc is required for bone growth and homeostasis and is also a crucial cofactor for numerous proteins that play key roles in maintaining microstructural integrity and bone remodeling. Bone marrow-derived mesenchymal stem cells (BMSCs) are multipotent progenitors found in the bone marrow stroma and can differentiate along multiple lineage pathways.
View Article and Find Full Text PDFHeliyon
October 2024
Department of Materials Science and Engineering, Faculty of Mechanical Engineering, Budapest University of Technology and Economics, Műegyetem Rkp. 3., H-1111, Budapest, Hungary.
Bimodal composite metal foams made from Al99.5 aluminium and quasi-eutectic Sr-modified AlSi12 matrix were investigated, where the bimodality was introduced by two alumina hollow sphere sets with nominal diameters of Ø7.0 and Ø2.
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