Background: Chronic exertional compartment syndrome (CECS) of the lower limb usually responds well to fasciotomy in patients with failed nonoperative treatment. Careful history taking and compartment pressure testing are both required to accurately diagnose CECS.
Purposes: To evaluate patients with CECS after fasciotomy to establish predictive criteria of positive outcomes and to develop a scoring system to aid clinicians in their management of such patients.
Study Design: Case-control study; Level of evidence, 3.
Methods: We reviewed data from 28 patients who underwent fasciotomy between 2017 and 2019. All patients had undergone preoperative dynamic intracompartmental pressure (ICP) monitoring. For each patient, subjective preoperative and postoperative pain scores were gained via a questionnaire. The point biserial and Pearson correlation coefficients were used to calculate the association between multiple diagnostic criteria and a reduction in visual analog scale (VAS) pain scores after fasciotomy.
Results: A reduction in VAS pain scores was strongly correlated with a peak ICP >40 mm Hg ( = 0.71; = .0007) and an area under the receiver operating characteristic curve for an intraexercise ICP >22,000 mm Hg·s ( = 0.76; = .0002). A moderate correlation was found between a history of CECS pain ( = 0.61; = .005), a duration of symptoms of <30 minutes after stopping exercise ( = 0.60; = .006), and a gradient in the intraexercise ICP >10 mm Hg ( = 0.60; = .006). When combined into an objective, weighted scoring system (2 points for factors with > 0.7; 1 point for = 0.5-0.7), a score of ≥4 points (of 7) had a strong correlation ( = 0.85; < .00001) with postoperative improvement in the VAS pain score. Linear regression of this score demonstrated a good fit ( = 0.61; < .0001), indicating a degree of predictive power.
Conclusion: We identified diagnostic criteria in the history and examination of patients with CECS that can be used to help predict positive outcomes after fasciotomy. We propose a scoring system to aid clinicians in their management of such patients. We recommend taking these results forward in prospective trials to test the efficacy of predictive scoring.
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http://dx.doi.org/10.1177/23259671221101328 | DOI Listing |
Int J Surg
January 2025
Department of General, Visceral, and Transplant Surgery, Ludwig-Maximilians-University Munich, Germany.
Objectives: Every year, around 300 million surgeries are conducted worldwide, with an estimated 4.2 million deaths occurring within 30 days after surgery. Adequate patient education is crucial, but often falls short due to the stress patients experience before surgery.
View Article and Find Full Text PDFJ Nurs Scholarsh
January 2025
Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia, USA.
Introduction: Adverse childhood experiences (ACEs) are associated with an increased risk of developing chronic health conditions, including Alzheimer's disease and related dementias (ADRD) and subjective cognitive decline (SCD), self-reported confusion/memory loss, and an early clinical manifestation of ADRD. While ACEs and SCD have both been individually studied in transgender and nonbinary (TGN) adults, no study has examined the relationship between the two among this population. This study sought to establish the prevalence of ACEs and their association with SCD among TGN adults.
View Article and Find Full Text PDFCoron Artery Dis
January 2025
Department of Medicine, Lundquist Institute at Harbor-UCLA Medical Center, Los Angeles.
Background: Coronary artery dominance is determined by the coronary artery emitting the posterior descending artery. In the left dominant system, a greater proportion of coronary flow enters the left coronary artery, potentially influencing calcified plaque development in the left anterior descending artery (LAD).
Methods: This retrospective single-center cohort study analyzed patients who underwent computed tomography angiography from September 2006 to December 2022 at Harbor-UCLA in Los Angeles, California.
Gigascience
January 2025
Leibniz Institute for the Analysis of Biodiversity Change, Museum Koenig Bonn, 53113 Bonn, Germany.
Background: In this study, we present an in-depth analysis of the Eurasian minnow (Phoxinus phoxinus) genome, highlighting its genetic diversity, structural variations, and evolutionary adaptations. We generated an annotated haplotype-phased, chromosome-level genome assembly (2n = 50) by integrating high-fidelity (HiFi) long reads and chromosome conformation capture data (Hi-C).
Results: We achieved a haploid size of 940 megabase pairs (Mbp) for haplome 1 and 929 Mbp for haplome 2 with high scaffold N50 values of 36.
Front Public Health
January 2025
Orcasitas Health Care Center, Madrid, Spain.
Introduction: Functional dependence on the performance of basic activities of daily living (ADLs) is associated with increased mortality. In this study, the Barthel index and its activities discriminate long-term mortality risk, and whether changes in this index are necessary to adapt it to detect mortality risk is examined.
Methods: Longitudinal study, carried out at the Orcasitas Health Center, Madrid (Spain), on the functional dependent population (Barthel ≤ 60).
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