Granulomatous mastitis is a rare benign disease that typically occurs in parous women. Some reports have described cases of erythema nodosum appearing following granulomatous mastitis, which is often treated with steroids. Here, we report a case of granulomatous mastitis with erythema nodosum successfully treated via drainage only, which may have been caused by the higher plasma cortisol levels observed during pregnancy. Although mastitis is rare during pregnancy, the current case suggests that granulomatous mastitis should be considered in pregnant women with treatment-resistant mastitis, especially in those with erythema nodosum and a history of birth. Furthermore, patients with granulomatous mastitis may not require prednisolone treatment during pregnancy, which may help in preventing steroid-associated conditions such as infections and gestational diabetes mellitus.
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http://dx.doi.org/10.7759/cureus.24990 | DOI Listing |
Cureus
December 2024
Oncology/Radiation Oncolgy, Tawam Hospital, Al Ain, ARE.
Granulomatous mastitis (GM) is a chronic inflammatory breast condition that presents significant diagnostic challenges due to its clinical and imaging similarities to malignancies. Accurate diagnosis is crucial to avoid unnecessary interventions and ensure effective management. A total of 1,216 articles were initially identified through a comprehensive database search.
View Article and Find Full Text PDFArch Pathol Lab Med
January 2025
From the Divisions of Pathology and Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas (Gan, Y Ding, Wu, Zhang, Meng, QQ Ding, Han).
Objective.—: To report the isolation and significance of C kroppenstedtii, features of patients with GLM, pathologic findings and mechanism, bacteriologic workup, and optimal treatment.
Design.
Int J Mol Sci
January 2025
Department of Molecular Medicine, Aziz Sancar Institute of Experimental Medicine, Istanbul University, 34093 Istanbul, Türkiye.
Granulomatous mastitis (GM) is a rare, benign, but chronic and recurrent inflammatory breast disease that significantly impacts physical and psychological well-being. It often presents symptoms such as pain, swelling, and discharge, leading to diagnostic confusion with malignancy. The etiology of GM remains unclear, though autoimmune and multifactorial components are suspected.
View Article and Find Full Text PDFRheumatol Int
January 2025
Division of Rheumatology, Centre hospitalier de l'Université de Montréal (CHUM), Department of Medicine, Université de Montréal, Montreal, Canada.
Idiopathic granulomatous mastitis (IGM) is a rare inflammatory disease of the breast. Various clinical management approaches have been described, but their efficacy and optimal sequential order remain uncertain. We describe the first Canadian cohort of patients with IGM, discuss treatment outcomes and outline a practical management approach.
View Article and Find Full Text PDFJ Infect Chemother
January 2025
Department of Infectious Diseases, Hiroshima University Hospital, Hiroshima, 734-8551, Japan.
Corynebacterium species are an important cause of granulomatous mastitis (GM). Although there have been worldwide reports of infections caused by Corynebacterium kroppenstedtii, few cases of C. tuberculostearicum GM have been reported.
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