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Epidemiological characteristics and prediction model construction of hand, foot and mouth disease in Quzhou City, China, 2005-2023.
Front Public Health
January 2025
Department of Immunity, Quzhou Center for Disease Control and Prevention, Quzhou, Zhejiang, China.
Background: HFMD is a common infectious disease that is prevalent worldwide. In many provinces in China, there have been outbreaks and epidemics of whooping cough, posing a threat to public health.
Purpose: It is crucial to grasp the epidemiological characteristics of HFMD in Quzhou and establish a prediction model for HFMD to lay the foundation for early warning of HFMD.
Correction to: Estimating the influence of high temperature on hand, foot, and mouth disease incidence in China.
Environ Sci Pollut Res Int
January 2025
Shandong Center for Disease Control and Prevention, Jinan, 250014, China.
Anatomical basis and clinical application of the dorsal metacarpal cutaneous branch flap of radial digital artery of index finger.
Surg Radiol Anat
December 2024
Department of Hand-Foot Microsurgery, Shenzhen Nanshan People's Hospital, No. 89 Taoyuan Road, Nanshan District, Shenzhen, 518052, China.
Objective: This study explored the surgical technique and clinical application of the dorsal metacarpal cutaneous branch flap of the radial digital artery of the index finger.
Methods: Through the anatomical dissection of 10 hand specimens, we examined the origin and characteristics of the artery and its branches towards the hand dorsum. Furthermore, the soft tissue defects of the index finger in 12 patients admitted to our hospital between 2017 and 2021 were surgically repaired using the dorsal metacarpal cutaneous branch flap of the radial digital artery of the index finger.
Discovery of a broad-spectrum monoclonal antibody recognizing a conserved, linear epitope WFYDGYPT on VP1 protein of Enterovirus A species.
Virol J
December 2024
Wuhan Institute of Biological Products Co., Ltd.,, No.1 Huangjin Industrial Park Road, Jiangxia District, Wuhan, 430207, China.
Background: The hand, foot and mouth disease (HFMD) was caused by species of Enterovirus A and Enterovirus B in the Asian-Pacific region. Broad-spectrum monoclonal antibodies (mAb) that can bind multiple serotypes of enteroviruses have gradually become a research hotspot in the diagnosis, prevention and treatment of HFMD.
Methods: In this study, a mAb 1H4 was obtained using monoclonal antibody technology by immunizing purified virus particles of Coxsackievirus A5 (CV-A5).
Arginine depletion-induced autophagy and metabolic dysregulation are involved in the disease severity of hand, foot, and mouth disease.
Virulence
December 2025
Department of Epidemiology, College of Public Health, Zhengzhou University, Zhengzhou, Henan, China.
Amino acid metabolism provides significant insight into the development and prevention of many viral diseases. Therefore, the present study aimed to compare the amino acid profiles of hand, foot, and mouth disease (HFMD) patients with those of healthy individuals and to further reveal the molecular mechanisms of HFMD severity. Using UPLC-MS/MS, we determined the plasma amino acid expression profiles of pediatric patients with HFMD (mild, = 42; severe, = 43) and healthy controls ( = 25).
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