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Boosting efficiency in a clinical literature surveillance system with LightGBM.
PLOS Digit Health
September 2024
Health Information Research Unit, Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, Ontario, Canada.
Given the suboptimal performance of Boolean searching to identify methodologically sound and clinically relevant studies in large bibliographic databases, exploring machine learning (ML) to efficiently classify studies is warranted. To boost the efficiency of a literature surveillance program, we used a large internationally recognized dataset of articles tagged for methodological rigor and applied an automated ML approach to train and test binary classification models to predict the probability of clinical research articles being of high methodologic quality. We trained over 12,000 models on a dataset of titles and abstracts of 97,805 articles indexed in PubMed from 2012-2018 which were manually appraised for rigor by highly trained research associates and rated for clinical relevancy by practicing clinicians.
View Article and Find Full Text PDFETV6 Molecular Heterogeneity in Salivary Secretory Carcinoma: A Case Series Report and Literature Review.
Head Neck Pathol
August 2024
Department of Molecular Medicine and Haematology, National Health Laboratory Services, School of Pathology, Faculty of Health Sciences, University of the Witwatersrand, Johannesburg, South Africa.
Background: ETV6 gene rearrangement is the molecular hallmark of secretory carcinoma (SC), however; the nature, frequency, and clinical implications of atypical ETV6 signal patterns by fluorescence in situ hybridization (FISH) has not yet been systematically evaluated in salivary gland neoplasms.
Methods: The clinical, histopathologic, immunohistochemical and molecular features of seven salivary SCs, including four cases with atypical ETV6 FISH patterns, were retrospectively analyzed along with a critical appraisal of the literature on unbalanced ETV6 break-apart in SCs.
Results: The patients were four males and three females (31-70 years-old).
Impact of fiscal decentralization and local government competition on the supply of basic public services: Based on the empirical evidence of prefecture-level cities in China.
Heliyon
February 2024
Faculty of Humanities and Social Sciences, Macao Polytechnic University, Macao, 999078, China.
Promoting equal access to public services and improving people's well-being is a key link in building a modern national governance system in China. However, under the Chinese-style fiscal decentralization system, local governments face the "dilemma" of economic growth goals and the improvement of people's livelihoods. China's basic public services still have the problems of insufficient supply quantity, unbalanced structure and low efficiency.
View Article and Find Full Text PDFEvidence-based appraisal of the role of SJTs in selection.
Clin Med (Lond)
December 2023
Hull York Medical School, University of York, York, UK.
A recent opinion article in promoted a new preference-based algorithm to allocate training places for the UK Foundation Programme Office (UKFPO). This replaced the previous process, which ranked candidates based on medical school academic achievement (the educational performance measure; EPM) and the score on a situational judgement test (SJT). Although not without risks, we believe that the new system has positive potential.
View Article and Find Full Text PDFEvidence-based practice in undergraduate physiotherapy programs in Brazil: A cross-sectional document analysis study.
Physiother Res Int
January 2024
Department of Biological Sciences and Health, Federal University of Amapá - UNIFAP, Macapá, AP, Brazil.
Article Synopsis
- Most undergraduate physiotherapy programs in Brazil lack courses on evidence-based practice (EBP), with only 9.4% offering such courses and an average duration of 44.3 hours.
- There is a regional disparity, with the North region providing a higher percentage of EBP courses despite fewer overall programs compared to the Southeast.
- The study highlights a need for improved EBP incorporation in curricula to enhance the training and decision-making abilities of future physiotherapists in Brazil.
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