A PHP Error was encountered

Severity: Warning

Message: file_get_contents(https://...@pubfacts.com&api_key=b8daa3ad693db53b1410957c26c9a51b4908&a=1): Failed to open stream: HTTP request failed! HTTP/1.1 429 Too Many Requests

Filename: helpers/my_audit_helper.php

Line Number: 176

Backtrace:

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 176
Function: file_get_contents

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 250
Function: simplexml_load_file_from_url

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 1034
Function: getPubMedXML

File: /var/www/html/application/helpers/my_audit_helper.php
Line: 3152
Function: GetPubMedArticleOutput_2016

File: /var/www/html/application/controllers/Detail.php
Line: 575
Function: pubMedSearch_Global

File: /var/www/html/application/controllers/Detail.php
Line: 489
Function: pubMedGetRelatedKeyword

File: /var/www/html/index.php
Line: 316
Function: require_once

Univariate or multivariate approaches for histopathological biomarkers in the context of environmental quality assessments? | LitMetric

AI Article Synopsis

  • The study highlights the drawback of simplifying complex histopathological data into single indices, which can result in significant information loss regarding environmental quality.
  • The research aimed to assess the effectiveness of a multivariate approach that combines individual histopathological responses with contaminant levels, comparing it to the traditional univariate Bernet index.
  • Results showed that the multivariate analysis provided a clearer classification of environmental quality across various sites, while the univariate index was less reliable and primarily identified only the most severely impacted areas.

Article Abstract

Although the simplification of multivariate histopathological data into univariate indices can be useful for the assessment of environmental quality, this implies a great loss of information. The objective of the present study was to evaluate the effectiveness, in the context of environmental quality assessment, of an approach that integrates individual histopathological responses in a discriminated manner with the results of contaminants by means of multivariate analyses. This analysis was compared to the diagnosis of environmental quality provided by the use of the univariate Bernet histopathological index. Contaminant loads (sediments and fish) and the liver histopathology of Cathorops spixii were integrated through multivariate analysis. Integrated individual histopathological responses allowed classifying environmental quality from more to less impacted sites, while the univariate index showed some inconsistencies with chemical loads and allowed identifying only the most impacted site.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.marpolbul.2022.113828DOI Listing

Publication Analysis

Top Keywords

environmental quality
20
context environmental
8
individual histopathological
8
histopathological responses
8
histopathological
5
environmental
5
quality
5
univariate
4
univariate multivariate
4
multivariate approaches
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!