AI Article Synopsis
- Tumor cells produce extracellular vesicles (EVs) that carry various molecules and significantly influence the progression of diseases like gliomas, which are common primary brain tumors.
- Glioblastoma multiforme (GBM), a severe type of grade IV glioma, remains difficult to treat despite improved diagnostic and therapeutic techniques.
- Recent research highlights the role of EVs in glioma growth and their potential applications in diagnostics, prognostics, and treatment strategies for gliomas.
Article Abstract
EV produced by tumour cells carry a diverse population of proteins, lipids, DNA, and RNA molecules throughout the body and appear to play an important role in the overall development of the disease state, according to growing data. Gliomas account for a sizable fraction of all primary brain tumours and the vast majority of brain malignancies. Glioblastoma multiforme (GBM) is a kind of grade IV glioma that has a very dismal prognosis despite advancements in diagnostic methods and therapeutic options. The authors discuss advances in understanding the function of extracellular vesicles (EVs), in overall glioma growth, as well as how recent research is uncovering the utility of EVs in glioma diagnostics, prognostic and therapeutics approaches.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9206693 | PMC |
| http://dx.doi.org/10.1007/s12672-022-00514-0 | DOI Listing |
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