Objective: This study aimed to explore the autobiographical foundations of specific narrative identities, which made it possible to choose medical volunteering in the time of the pandemic, resist highly hazardous conditions of working in COVID-19 "red zones," and emerge from this work with a sense of meaning and optimism.
Method: In this study, we focused on the graphical life stories, self-defining memories (SDMs), and self-defining future projections (SDFPs) of four individuals who worked at COVID-19 "red zone" hospitals as medical volunteers.
Results: The analysis revealed that all participants incorporated their volunteering experiences as meaningful and satisfying into their general narrative identity. They scored high on standard scales assessing subjective well-being and reported autonomous regulation of volunteer motivation. We identified narrative trunk lines and metaphors across autobiographical data, which differentiated the participants into four types of general identities extensively manifesting in volunteering identity: faith-based, influence-based, help-based, and success-based. The participants' graphical life stories, SDMs, and SDFPs showed similar patterns consisting of adult-oriented childhood, focus on mid-life events, and a redemption sequence in narration.
Conclusion: These findings could be taken as touchstones to highlight the critical value of self-continuity and sense of purpose in active coping with global challenges.
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http://dx.doi.org/10.1111/jopy.12747 | DOI Listing |
Previous RNA profiling studies revealed co-expression of overlapping sense/antisense (s/a) transcripts in pro- and eukaryotic organisms. Functional analyses in yeast have shown that certain s/a mRNA/mRNA and mRNA/lncRNA pairs form stable double-stranded RNAs (dsRNAs) that affect transcript stability. Little is known, however, about the genome-wide prevalence of dsRNA formation and its potential functional implications during growth and development in diploid budding yeast.
View Article and Find Full Text PDFAdv Nutr
January 2025
Centro de Investigación Biomédica en Red Fisiopatología de la Obesidad y la Nutrición (CIBEROBN), Instituto de Salud Carlos III (ISCIII), Madrid, Spain; Department of Internal Medicine, Institut d'Investigacions Biomèdiques August Pi Sunyer (IDIBAPS), Hospital Clinic, University of Barcelona (UB), Barcelona, Spain; Institut de Recerca en Nutrició i Seguretat Alimentaria (INSA-UB). University of Barcelona, Barcelona, Spain; Fundación Dieta Mediterránea, Barcelona, Spain. Electronic address:
Cardiovascular risk factors begin in childhood and track into adulthood, increasing the possibility of impaired cardiometabolic health. Adopting healthy dietary patterns can help curb childhood obesity, a worrisome epidemic problem at present. In the era of personalized nutrition, dietary recommendations should be adapted to different stages of life, including children (older than 3 years) and adolescents.
View Article and Find Full Text PDFJ Med Internet Res
January 2025
Department of Electrical Engineering, Chalmers University of Technology, Gothenburg, Sweden.
Background: The aging global population and the rising prevalence of chronic disease and multimorbidity have strained health care systems, driving the need for expanded health care resources. Transitioning to home-based care (HBC) may offer a sustainable solution, supported by technological innovations such as Internet of Medical Things (IoMT) platforms. However, the full potential of IoMT platforms to streamline health care delivery is often limited by interoperability challenges that hinder communication and pose risks to patient safety.
View Article and Find Full Text PDFStat Med
February 2025
Programme in Health Services & Systems Research, Duke-NUS Medical School, National University of Singapore, Singapore, Singapore.
Incidence of adverse outcome events rises as patients with advanced illness approach end-of-life. Exposures that tend to occur near end-of-life, for example, use of wheelchair, oxygen therapy and palliative care, may therefore be found associated with the incidence of the adverse outcomes. We propose a concept of reverse time-to-death (rTTD) and its use for the time-scale in time-to-event analysis based on partial likelihood to mitigate the time-varying confounding.
View Article and Find Full Text PDFCell Biochem Biophys
January 2025
Division of Biomedical and Life Sciences, School of Science, Navrachana University, Vadodara, Gujarat, India.
Cancer Stem Cells (CSCs) play an important role in the development, resistance, and recurrence of many malignancies. These subpopulations of tumor cells have the potential to self-renew, differentiate, and resist conventional therapy, highlighting their importance in cancer etiology. This review explores the regulatory mechanisms of CSCs in breast, cervical, and lung cancers, highlighting their plasticity, self-renewal, and differentiation capabilities.
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